Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits
Dental implants are widely recognized for their effectiveness in restoring missing teeth, yet their success is often compromised by infections or inadequate osseointegration. Propolis, a natural resinous substance with potent antimicrobial, anti-inflammatory, and osteogenic properties, has emerged a...
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MDPI AG
2024-11-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | https://www.mdpi.com/2079-4983/15/11/339 |
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| author | Magdalena Sycińska-Dziarnowska Liliana Szyszka-Sommerfeld Magdalena Ziąbka Krzysztof Woźniak Gianrico Spagnuolo |
| author_facet | Magdalena Sycińska-Dziarnowska Liliana Szyszka-Sommerfeld Magdalena Ziąbka Krzysztof Woźniak Gianrico Spagnuolo |
| author_sort | Magdalena Sycińska-Dziarnowska |
| collection | DOAJ |
| description | Dental implants are widely recognized for their effectiveness in restoring missing teeth, yet their success is often compromised by infections or inadequate osseointegration. Propolis, a natural resinous substance with potent antimicrobial, anti-inflammatory, and osteogenic properties, has emerged as a promising adjunct in dental implantology. This systematic review critically evaluates the current evidence on the incorporation of propolis into dental implants, focusing on its impact on antimicrobial efficacy, bone healing, and overall implant stability. The study protocol was registered in PROSPERO under the registration number CRD42024577122. The PRISMA diagram visually represented the search strategy, screening, and inclusion process. Two reviewers conducted a comprehensive literature search across five databases: PubMed, PubMed Central, Embase, Scopus, and Web of Science. The review synthesized findings from 13 studies; in vitro, in vivo, and clinical studies, highlighting that propolis significantly enhances antibacterial and antifungal activities against pathogens such as <i>Staphylococcus aureus</i>, <i>Candida albicans</i>, and <i>Streptococcus mutans</i>, thereby reducing the risk of peri-implant infections. Additionally, propolis promotes osseointegration by stimulating osteoblast activity and reducing inflammatory cytokine expression, leading to improved bone formation and implant stability. The anti-inflammatory and antioxidant properties of propolis further contribute to a favorable healing environment, enhancing the long-term success of dental implants. The systematic review underscores the potential of propolis as a safe, biocompatible, and effective material for improving dental implant outcomes. However, it also identifies the need for more extensive clinical trials to fully establish standardized protocols for propolis application in implantology. This review provides an overview of propolis’s potential role in dental implants and suggests promising avenues for future research to optimize its benefits in clinical practice. |
| format | Article |
| id | doaj-art-a59b27f7e7644bd5880aad461efd9ac6 |
| institution | Kabale University |
| issn | 2079-4983 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj-art-a59b27f7e7644bd5880aad461efd9ac62024-11-26T18:07:33ZengMDPI AGJournal of Functional Biomaterials2079-49832024-11-01151133910.3390/jfb15110339Propolis in Dental Implantology: A Systematic Review of Its Effects and BenefitsMagdalena Sycińska-Dziarnowska0Liliana Szyszka-Sommerfeld1Magdalena Ziąbka2Krzysztof Woźniak3Gianrico Spagnuolo4Department of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, PolandDepartment of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, PolandFaculty of Materials Science and Ceramics, Department of Ceramics and Refractories, AGH University of Krakow, 30059 Krakow, PolandDepartment of Maxillofacial Orthopaedics and Orthodontics, Pomeranian Medical University in Szczecin, Al. Powst. Wlkp. 72, 70111 Szczecin, PolandDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, 80131 Napoli, ItalyDental implants are widely recognized for their effectiveness in restoring missing teeth, yet their success is often compromised by infections or inadequate osseointegration. Propolis, a natural resinous substance with potent antimicrobial, anti-inflammatory, and osteogenic properties, has emerged as a promising adjunct in dental implantology. This systematic review critically evaluates the current evidence on the incorporation of propolis into dental implants, focusing on its impact on antimicrobial efficacy, bone healing, and overall implant stability. The study protocol was registered in PROSPERO under the registration number CRD42024577122. The PRISMA diagram visually represented the search strategy, screening, and inclusion process. Two reviewers conducted a comprehensive literature search across five databases: PubMed, PubMed Central, Embase, Scopus, and Web of Science. The review synthesized findings from 13 studies; in vitro, in vivo, and clinical studies, highlighting that propolis significantly enhances antibacterial and antifungal activities against pathogens such as <i>Staphylococcus aureus</i>, <i>Candida albicans</i>, and <i>Streptococcus mutans</i>, thereby reducing the risk of peri-implant infections. Additionally, propolis promotes osseointegration by stimulating osteoblast activity and reducing inflammatory cytokine expression, leading to improved bone formation and implant stability. The anti-inflammatory and antioxidant properties of propolis further contribute to a favorable healing environment, enhancing the long-term success of dental implants. The systematic review underscores the potential of propolis as a safe, biocompatible, and effective material for improving dental implant outcomes. However, it also identifies the need for more extensive clinical trials to fully establish standardized protocols for propolis application in implantology. This review provides an overview of propolis’s potential role in dental implants and suggests promising avenues for future research to optimize its benefits in clinical practice.https://www.mdpi.com/2079-4983/15/11/339propolisdental implantsantimicrobial |
| spellingShingle | Magdalena Sycińska-Dziarnowska Liliana Szyszka-Sommerfeld Magdalena Ziąbka Krzysztof Woźniak Gianrico Spagnuolo Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits Journal of Functional Biomaterials propolis dental implants antimicrobial |
| title | Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits |
| title_full | Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits |
| title_fullStr | Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits |
| title_full_unstemmed | Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits |
| title_short | Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits |
| title_sort | propolis in dental implantology a systematic review of its effects and benefits |
| topic | propolis dental implants antimicrobial |
| url | https://www.mdpi.com/2079-4983/15/11/339 |
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