STRUCTURAL FEATURES OF ADAPTIVE HEART PROTECTION IN ACUTE MYOCARDIAL ISCHEMIA AND INFARCTION
We have used stereo- and morphometric studies to examine the influence of the three ways of preliminary adaptation on the size of ischemia and infarction foci, as well as the condition of right atrium and non-ischemic areas, in experimental coronary occlusion. We have found that despite a lack of an...
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| Main Author: | |
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| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2001-06-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2133 |
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| Summary: | We have used stereo- and morphometric studies to examine the influence of the three ways of preliminary adaptation on the size of ischemia and infarction foci, as well as the condition of right atrium and non-ischemic areas, in experimental coronary occlusion. We have found that despite a lack of anti-ischemic effect, preliminary adaptation to a short-lasting stress exhibits a marked beneficial impact at the nectrotic and non-ischemic areas. In animals adapted to physical stress, a moderate anti-ischemic effect with a potent antinecrotic and an even more observed influence on the non-ischemic areas of the myocardium. Adaptation to mild hypoxia possesses a moderate anti-ischemic influence combined with a liewise moderate effect on the necrotic and non-ischemic areas. All kinds of adaptation exert a beneficial effect on mortality rates in animals with coronary occlusion. |
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| ISSN: | 1560-4071 2618-7620 |