The inflammasome-activating poxvirus peptide IAMP29 promotes antimicrobial and anticancer responses

Abstract Poxviruses are implicated in a variety of infectious diseases; however, little is known about the molecular mechanisms that underlie the immune response during poxvirus infection. We investigated the function and mechanisms of the monkeypox virus envelope protein (A30L) and its core peptide...

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Main Authors: Taylor Roh, Wonhyoung Seo, Minho Won, Woo Seok Yang, Asmita Sapkota, Eun-Jin Park, Sung-Ho Yun, Sang Min Jeon, Kyung Tae Kim, Bomi Lee, Gyoungah Ryu, Sang-Hee Lee, Jung-Min Shin, Hyo Jung Shin, Young Jae Kim, Young Lee, Chaeuk Chung, Ik-Chan Song, Hyun Kyu Song, Eun-Kyeong Jo
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01339-3
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