Lesson learned in pediatric haploidentical transplantation in a low-resource environment: delivering melphalan IV and using low dose radiation reduce graft failure

Lesson learned in pediatric haploidentical transplantation in a low-resource environment: delivering melphalan IV and using low dose radiation reduce graft failure

Objectives: Primary graft failure (pGF) after hematopoietic stem-cell transplant is associated with considerable morbidity and mortality. The incidence in haplo-HSCT has been reported to be between 0% and 30%. In 2018, we identified a pGF incidence of 35% in our pediatric haplo-HSCT recipients with...

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Bibliographic Details
Main Authors: Valentine Jiménez-Antolinez, Julia Colunga-Pedraza, Andrés Gómez-De León, Elias González-Lopez, David Gómez-Almaguer, Oscar González-Llano
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
Subjects:
Haploidentical
Primary graft failure
Pediatric
Conditioning regimen
Melphalan
TBI
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2024.2335417
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https://www.tandfonline.com/doi/10.1080/16078454.2024.2335417

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