Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study

Background:Coronary artery disease (CAD) is a major cause of cardiovascular mortality. Echocardiography plays a vital role in early detection and treatment. Objectives:We investigated the use of speckle tracking during dobutamine stress echocardiography (DSE) to diagnose CAD in moderate-risk patient...

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Main Authors: Marwa Majeed Kadhim, Shokry F. AL-Saad, Hassan Salim Al-Jumaily, Zainab Falah Hassan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-09-01
Series:Medical Journal of Babylon
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Online Access:https://journals.lww.com/10.4103/MJBL.MJBL_1300_23
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author Marwa Majeed Kadhim
Shokry F. AL-Saad
Hassan Salim Al-Jumaily
Zainab Falah Hassan
author_facet Marwa Majeed Kadhim
Shokry F. AL-Saad
Hassan Salim Al-Jumaily
Zainab Falah Hassan
author_sort Marwa Majeed Kadhim
collection DOAJ
description Background:Coronary artery disease (CAD) is a major cause of cardiovascular mortality. Echocardiography plays a vital role in early detection and treatment. Objectives:We investigated the use of speckle tracking during dobutamine stress echocardiography (DSE) to diagnose CAD in moderate-risk patients. Materials and Methods:A 4-month cross-sectional study enrolled 42 moderate-risk patients without prior CAD history. Data included questionnaires, echocardiographic measurements, and SPSS analysis. Results:Patients were divided into CAD-negative (66.7%) and CAD-positive (33.3%) groups based on coronary angiography. Speckle tracking during stress correlated better with angiography (kappa = 0.78) than at rest (kappa = 0.21) or stress visualization (kappa = 0.66). Sensitivity and specificity were 71.4% and 92.8% (stress test), 57.1% and 85.7% (speckle at rest), and 85.7% and 92.8% (speckle during stress), respectively. Conclusion:Speckle tracking during DSE is a promising approach for diagnosing CAD in moderate-risk patients, enhancing early intervention possibilities.
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publishDate 2024-09-01
publisher Wolters Kluwer Medknow Publications
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series Medical Journal of Babylon
spelling doaj-art-a576347c24f54793b3f9efba02089ead2024-11-13T10:03:41ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602024-09-0121362162610.4103/MJBL.MJBL_1300_23Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative StudyMarwa Majeed KadhimShokry F. AL-SaadHassan Salim Al-JumailyZainab Falah HassanBackground:Coronary artery disease (CAD) is a major cause of cardiovascular mortality. Echocardiography plays a vital role in early detection and treatment. Objectives:We investigated the use of speckle tracking during dobutamine stress echocardiography (DSE) to diagnose CAD in moderate-risk patients. Materials and Methods:A 4-month cross-sectional study enrolled 42 moderate-risk patients without prior CAD history. Data included questionnaires, echocardiographic measurements, and SPSS analysis. Results:Patients were divided into CAD-negative (66.7%) and CAD-positive (33.3%) groups based on coronary angiography. Speckle tracking during stress correlated better with angiography (kappa = 0.78) than at rest (kappa = 0.21) or stress visualization (kappa = 0.66). Sensitivity and specificity were 71.4% and 92.8% (stress test), 57.1% and 85.7% (speckle at rest), and 85.7% and 92.8% (speckle during stress), respectively. Conclusion:Speckle tracking during DSE is a promising approach for diagnosing CAD in moderate-risk patients, enhancing early intervention possibilities.https://journals.lww.com/10.4103/MJBL.MJBL_1300_23coronary artery diseasedobutamine stressechocardiographyglobal longitudinal strainmoderate risknoninvasive imagingspeckle tracking
spellingShingle Marwa Majeed Kadhim
Shokry F. AL-Saad
Hassan Salim Al-Jumaily
Zainab Falah Hassan
Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study
Medical Journal of Babylon
coronary artery disease
dobutamine stress
echocardiography
global longitudinal strain
moderate risk
noninvasive imaging
speckle tracking
title Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study
title_full Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study
title_fullStr Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study
title_full_unstemmed Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study
title_short Role of Dobutamine Stress Test and Speckle Tracking in Ischemic Heart Disease, Comparative Study
title_sort role of dobutamine stress test and speckle tracking in ischemic heart disease comparative study
topic coronary artery disease
dobutamine stress
echocardiography
global longitudinal strain
moderate risk
noninvasive imaging
speckle tracking
url https://journals.lww.com/10.4103/MJBL.MJBL_1300_23
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AT shokryfalsaad roleofdobutaminestresstestandspeckletrackinginischemicheartdiseasecomparativestudy
AT hassansalimaljumaily roleofdobutaminestresstestandspeckletrackinginischemicheartdiseasecomparativestudy
AT zainabfalahhassan roleofdobutaminestresstestandspeckletrackinginischemicheartdiseasecomparativestudy