Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease
BackgroundLiver transplantation (LT) improves survival in end-stage liver disease. Several reports have addressed the impact of LT on patients’ lives, beyond purely medical outcomes. Although the quality of life and mental health have been demonstrated to improve with this procedure, such studies ar...
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| Format: | Article |
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Transplantation |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/frtra.2024.1476952/full |
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| author | Rosana Cordoba-Alvarado Rosana Cordoba-Alvarado Valentina Romero-Fonnegra Nicolas Cortes-Mejia Nicolas Cortes-Mejia Diana Fernanda Bejarano-Ramirez Diana Fernanda Bejarano-Ramirez Valentina Maldonado-Hoyos Sandra Janeth Sanchez-Garcia Alonso Vera-Torres Alonso Vera-Torres |
| author_facet | Rosana Cordoba-Alvarado Rosana Cordoba-Alvarado Valentina Romero-Fonnegra Nicolas Cortes-Mejia Nicolas Cortes-Mejia Diana Fernanda Bejarano-Ramirez Diana Fernanda Bejarano-Ramirez Valentina Maldonado-Hoyos Sandra Janeth Sanchez-Garcia Alonso Vera-Torres Alonso Vera-Torres |
| author_sort | Rosana Cordoba-Alvarado |
| collection | DOAJ |
| description | BackgroundLiver transplantation (LT) improves survival in end-stage liver disease. Several reports have addressed the impact of LT on patients’ lives, beyond purely medical outcomes. Although the quality of life and mental health have been demonstrated to improve with this procedure, such studies are still missing in Latin America.MethodsPatients who received LT at the Fundación Santa Fe de Bogotá between 2017 and 2019 were assessed for quality of life (QoL), anxiety, and depression and they were followed up for one year after the procedure. Pre-transplant data were gathered at inclusion on the waiting list, while post-transplant data at 3- and 12 months after LT. European Quality of Life-5 Dimensions (EQ-5D) and European Quality of Life-Visual Analog Scale (EQ-VAS) instruments were used to evaluate QoL. The Hospital Anxiety and Depression Scale (HADS) was used for evaluating anxious and depressive symptoms.Results115 recipients met the inclusion criteria. Mean pre-transplant EQ-VAS was 70.78, rising to 87.16 and 92.56 at 3- and 12-months, respectively. Improvements in all EQ-5D dimensions were found in response to LT. According to the HADS questionnaire, anxiety was reduced by 2.35 points and depression by 1.63 points after LT.Conclusionin the short term, LT is a successful strategy for enhancing QoL, anxiety, and depression in patients with liver disease. Long-term benefits must be assessed. |
| format | Article |
| id | doaj-art-a4bb83a6f96240dfa24f1d3ae698e93c |
| institution | Kabale University |
| issn | 2813-2440 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Transplantation |
| spelling | doaj-art-a4bb83a6f96240dfa24f1d3ae698e93c2024-11-21T06:23:51ZengFrontiers Media S.A.Frontiers in Transplantation2813-24402024-11-01310.3389/frtra.2024.14769521476952Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver diseaseRosana Cordoba-Alvarado0Rosana Cordoba-Alvarado1Valentina Romero-Fonnegra2Nicolas Cortes-Mejia3Nicolas Cortes-Mejia4Diana Fernanda Bejarano-Ramirez5Diana Fernanda Bejarano-Ramirez6Valentina Maldonado-Hoyos7Sandra Janeth Sanchez-Garcia8Alonso Vera-Torres9Alonso Vera-Torres10Clinical Psychology Section, Transplant Services, Fundacion Santa Fe de Bogotá, Bogotá, ColombiaTransplant and Hepatobiliary Surgery Department, Fundación Santa Fe de Bogotá, Bogotá, ColombiaFaculty of Psychology, Universidad de los Andes, Bogotá, ColombiaTransplant and Hepatobiliary Surgery Department, Fundación Santa Fe de Bogotá, Bogotá, ColombiaDivision of Anesthesiology Critical Care Medicine, and Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United StatesTransplant and Hepatobiliary Surgery Department, Fundación Santa Fe de Bogotá, Bogotá, ColombiaEpidemiology and Biostatistics Group, Graduate School, Universidad CES, Medellín, ColombiaFaculty of Psychology, Universidad de los Andes, Bogotá, ColombiaClinical Psychology Section, Transplant Services, Fundacion Santa Fe de Bogotá, Bogotá, ColombiaTransplant and Hepatobiliary Surgery Department, Fundación Santa Fe de Bogotá, Bogotá, ColombiaFaculty of Medicine, Universidad de los Andes, Bogotá, ColombiaBackgroundLiver transplantation (LT) improves survival in end-stage liver disease. Several reports have addressed the impact of LT on patients’ lives, beyond purely medical outcomes. Although the quality of life and mental health have been demonstrated to improve with this procedure, such studies are still missing in Latin America.MethodsPatients who received LT at the Fundación Santa Fe de Bogotá between 2017 and 2019 were assessed for quality of life (QoL), anxiety, and depression and they were followed up for one year after the procedure. Pre-transplant data were gathered at inclusion on the waiting list, while post-transplant data at 3- and 12 months after LT. European Quality of Life-5 Dimensions (EQ-5D) and European Quality of Life-Visual Analog Scale (EQ-VAS) instruments were used to evaluate QoL. The Hospital Anxiety and Depression Scale (HADS) was used for evaluating anxious and depressive symptoms.Results115 recipients met the inclusion criteria. Mean pre-transplant EQ-VAS was 70.78, rising to 87.16 and 92.56 at 3- and 12-months, respectively. Improvements in all EQ-5D dimensions were found in response to LT. According to the HADS questionnaire, anxiety was reduced by 2.35 points and depression by 1.63 points after LT.Conclusionin the short term, LT is a successful strategy for enhancing QoL, anxiety, and depression in patients with liver disease. Long-term benefits must be assessed.https://www.frontiersin.org/articles/10.3389/frtra.2024.1476952/fullquality of lifeEuropean Quality of Life-5 Dimensions (EQ-5D)European Quality of Life Visual Analog Scale (EQ-VAS)Hospital Anxiety and Depression Scale (HADS)liver transplantation (LT) |
| spellingShingle | Rosana Cordoba-Alvarado Rosana Cordoba-Alvarado Valentina Romero-Fonnegra Nicolas Cortes-Mejia Nicolas Cortes-Mejia Diana Fernanda Bejarano-Ramirez Diana Fernanda Bejarano-Ramirez Valentina Maldonado-Hoyos Sandra Janeth Sanchez-Garcia Alonso Vera-Torres Alonso Vera-Torres Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease Frontiers in Transplantation quality of life European Quality of Life-5 Dimensions (EQ-5D) European Quality of Life Visual Analog Scale (EQ-VAS) Hospital Anxiety and Depression Scale (HADS) liver transplantation (LT) |
| title | Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease |
| title_full | Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease |
| title_fullStr | Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease |
| title_full_unstemmed | Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease |
| title_short | Quality of life, anxiety, and depression improve at one-year after liver transplantation in patients with advanced liver disease |
| title_sort | quality of life anxiety and depression improve at one year after liver transplantation in patients with advanced liver disease |
| topic | quality of life European Quality of Life-5 Dimensions (EQ-5D) European Quality of Life Visual Analog Scale (EQ-VAS) Hospital Anxiety and Depression Scale (HADS) liver transplantation (LT) |
| url | https://www.frontiersin.org/articles/10.3389/frtra.2024.1476952/full |
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