Genetic association analysis of lipid-lowering drug target genes in chronic kidney disease

Genetic association analysis of lipid-lowering drug target genes in chronic kidney disease

ObjectiveThe impact of lipid-lowering medications on chronic kidney disease (CKD) remains a subject of debate. This Mendelian randomization (MR) study aims to elucidate the potential effects of lipid-lowering drug targets on CKD development.MethodsWe extracted 11 genetic variants encoding targets of...

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Bibliographic Details
Main Authors:	Yi Zhang, Guangyang Ou, Lei Peng, Jian Pan, Shaohua Zhang, Jianguo Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Endocrinology
Subjects:	chronic kidney disease lipid-lowering drug lipids Mendelian randomization analysis estimated glomerular filtration rate
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1434145/full
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