A new microtubule-stabilizing agent shows potent antiviral effects against African swine fever virus with no cytotoxicity

A new microtubule-stabilizing agent shows potent antiviral effects against African swine fever virus with no cytotoxicity

African swine fever virus (ASFV) is the causal agent of a fatal disease of domestic swine for which no effective antiviral drugs are available. Recently, it has been shown that microtubule-targeting agents hamper the infection cycle of different viruses. In this study, we conducted in silico screeni...

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Main Authors: Samvel Sirakanyan, Erik Arabyan, Astghik Hakobyan, Tamara Hakobyan, Garri Chilingaryan, Harutyun Sahakyan, Arsen Sargsyan, Grigor Arakelov, Karen Nazaryan, Roza Izmailyan, Liana Abroyan, Zaven Karalyan, Elina Arakelova, Elmira Hakobyan, Anush Hovakimyan, Andre Serobian, Marco Neves, João Ferreira, Fernando Ferreira, Hovakim Zakaryan
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
African swine fever virus
microtubule
tubulin
antivirals
screening
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1902751
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https://www.tandfonline.com/doi/10.1080/22221751.2021.1902751

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