Predicting the effectiveness of omalizumab in patients with refractory chronic rhinosinusitis with nasal polyps comorbid with asthma based on inflammatory biomarkers

Predicting the effectiveness of omalizumab in patients with refractory chronic rhinosinusitis with nasal polyps comorbid with asthma based on inflammatory biomarkers

Background: The treatment of refractory chronic rhinosinusitis with nasal polyps (CRSwNP) with omalizumab has been well studied based on clinical evaluation. Nevertheless, ideal quantitative or qualitative biomarkers for predicting a different response to biologics urgently need to be explored. We a...

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Bibliographic Details
Main Authors: Yutong Sima, MD, Ming Zheng, MD, Yan Zhao, PhD, Siqi Ge, PhD, Chengyao Liu, MD, Ping Wang, BS, Xiangdong Wang, MD, PhD, Luo Zhang, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:World Allergy Organization Journal
Subjects:
Chronic rhinosinusitis with nasal polyps
Omalizumab
Endotype
Prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455124001418
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