Protocol for generating high-fidelity proteomic profiles using DROPPS

Summary: Deep mass spectrometry-based proteomic profiling of rare cell populations has been constrained by sample input requirements. Here, we present a protocol for droplet-based one-pot preparation for proteomic samples (DROPPS), an accessible low-input platform that generates high-fidelity proteo...

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Bibliographic Details
Main Authors: Matthew Waas, Meinusha Govindarajan, Amanda Khoo, Charlotte Zuo, Aastha Aastha, Jilin He, Michael Woolman, Annie Ha, Brian Lin, Thomas Kislinger
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724005628
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