Multivalent display of VP28 on chimeric virus-like particles enhances binding to shrimp target tissues: A novel antiviral strategy against white spot syndrome virus

Multivalent display of VP28 on chimeric virus-like particles enhances binding to shrimp target tissues: A novel antiviral strategy against white spot syndrome virus

Background and Aim: White spot syndrome virus (WSSV) is a devastating pathogen in shrimp aquaculture, with viral protein 28 (VP28) playing a critical role in host cell attachment and entry. The extracellular domain of VP28 (residues 35–95) is immunogenic and essential for infection; however, its rec...

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Bibliographic Details
Main Authors: Somkid Jaranathummakul, Pitchanee Jariyapong, Orawan Thongsum, Supawich Boonkua, Charoonroj Chotwiwatthanakun, Monsicha Somrit, Somluk Asuvapongpatana, Attaboon Wathammawut, Wattana Weerachatyanukul
Format: Article
Language:English
Published: Veterinary World 2025-08-01
Series:Veterinary World
Subjects:
aquaculture vaccines
macrobrachium rosenbergii nodavirus
shrimp immunity
tissue binding
virus-like particles
viral protein 28
white spot syndrome virus
Online Access:https://www.veterinaryworld.org/Vol.18/August-2025/4.pdf
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