Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial

Background Although smartphone application for smoking cessation was considered a promising strategy, there were scarce studies on the combination of usual interventions and apps for smoking cessation in China. Our study aimed to evaluate the efficacy of the Cigarette-Burning application combined wi...

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Main Authors: Xiao-Wen Wei, Rui Qin, Yong-Zhuang Liu, Zhao Liu, An-Qi Cheng, Xin-Mei Zhou, Zheng Su, Zi-Yang Cui, Jin-Xuan Li, Liang Zhao, Dan Xiao, Chen Wang
Format: Article
Language:English
Published: SAGE Publishing 2024-11-01
Series:Digital Health
Online Access:https://doi.org/10.1177/20552076241297732
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author Xiao-Wen Wei
Rui Qin
Yong-Zhuang Liu
Zhao Liu
An-Qi Cheng
Xin-Mei Zhou
Zheng Su
Zi-Yang Cui
Jin-Xuan Li
Liang Zhao
Dan Xiao
Chen Wang
author_facet Xiao-Wen Wei
Rui Qin
Yong-Zhuang Liu
Zhao Liu
An-Qi Cheng
Xin-Mei Zhou
Zheng Su
Zi-Yang Cui
Jin-Xuan Li
Liang Zhao
Dan Xiao
Chen Wang
author_sort Xiao-Wen Wei
collection DOAJ
description Background Although smartphone application for smoking cessation was considered a promising strategy, there were scarce studies on the combination of usual interventions and apps for smoking cessation in China. Our study aimed to evaluate the efficacy of the Cigarette-Burning application combined with medication intervention for smoking cessation. Methods A parallel, open-label randomized clinical trial was conducted with a ratio of 1:1 allocation into the bupropion plus app group and bupropion group. All participants received bupropion intervention. Besides, participants in the bupropion plus app group were required to download and use the Cigarette-Burning app. Follow-up visits were conducted at weeks 1, 2, 4, 9, 12, and 24 after initiation of treatment. Results Four hundred participants were eventually included and analyzed from July 2019 to June 2021. The continuous abstinence rate at 9–12 weeks was significantly higher in the bupropion plus app group (39.5%) than in the bupropion group (27.5%) (OR = 1.64, 95% CI: 1.04–2.60, p  < .05). The similar result was found for the 24-week sustained abstinence rate. The results of subgroup analysis expressed that the 9–12 weeks continuous abstinence rate in the bupropion plus app group was significantly higher than the bupropion group when the age of participants ≥ 50, the education level was college and above, FTND scores > 5, age at starting smoking ≤ 18 ( p  < .05). Conclusions Our study found that the intervention combined with the Cigarette-Burning smartphone application is more effective than medication alone, and the application for smoking cessation could be an accessible complement to smoking cessation medication treatment.
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spelling doaj-art-a3a43b62b1fa4785b82b6c70be0d9a182024-11-25T09:03:27ZengSAGE PublishingDigital Health2055-20762024-11-011010.1177/20552076241297732Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trialXiao-Wen Wei0Rui Qin1Yong-Zhuang Liu2Zhao Liu3An-Qi Cheng4Xin-Mei Zhou5Zheng Su6Zi-Yang Cui7Jin-Xuan Li8Liang Zhao9Dan Xiao10Chen Wang11 National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China Department of Radiology, , Beijing, China , Harbin, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China Department of Geriatric Medicine, , Beijing, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Tobacco Control and Prevention of Respiratory Disease, Center of Respiratory Medicine, , Beijing, China School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaBackground Although smartphone application for smoking cessation was considered a promising strategy, there were scarce studies on the combination of usual interventions and apps for smoking cessation in China. Our study aimed to evaluate the efficacy of the Cigarette-Burning application combined with medication intervention for smoking cessation. Methods A parallel, open-label randomized clinical trial was conducted with a ratio of 1:1 allocation into the bupropion plus app group and bupropion group. All participants received bupropion intervention. Besides, participants in the bupropion plus app group were required to download and use the Cigarette-Burning app. Follow-up visits were conducted at weeks 1, 2, 4, 9, 12, and 24 after initiation of treatment. Results Four hundred participants were eventually included and analyzed from July 2019 to June 2021. The continuous abstinence rate at 9–12 weeks was significantly higher in the bupropion plus app group (39.5%) than in the bupropion group (27.5%) (OR = 1.64, 95% CI: 1.04–2.60, p  < .05). The similar result was found for the 24-week sustained abstinence rate. The results of subgroup analysis expressed that the 9–12 weeks continuous abstinence rate in the bupropion plus app group was significantly higher than the bupropion group when the age of participants ≥ 50, the education level was college and above, FTND scores > 5, age at starting smoking ≤ 18 ( p  < .05). Conclusions Our study found that the intervention combined with the Cigarette-Burning smartphone application is more effective than medication alone, and the application for smoking cessation could be an accessible complement to smoking cessation medication treatment.https://doi.org/10.1177/20552076241297732
spellingShingle Xiao-Wen Wei
Rui Qin
Yong-Zhuang Liu
Zhao Liu
An-Qi Cheng
Xin-Mei Zhou
Zheng Su
Zi-Yang Cui
Jin-Xuan Li
Liang Zhao
Dan Xiao
Chen Wang
Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial
Digital Health
title Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial
title_full Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial
title_fullStr Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial
title_full_unstemmed Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial
title_short Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial
title_sort efficacy of the cigarette burning application combined with medication intervention for smoking cessation in china a randomized controlled trial
url https://doi.org/10.1177/20552076241297732
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