Constructing adverse outcome pathway for per- and polyfluoroalkyl substances and retinoblastoma based on PI3K-AKT/MAPK signaling pathway
BackgroundExposure to per- and polyfluoroalkyl substances (PFAS) is associated with various cancers, and recent studies suggest it may also increase the risk of retinoblastoma (RB) in newborns. However, the pathogenic mechanisms remain unclear. ObjectiveBy constructing an adverse outcome pathway (AO...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Editorial Committee of Journal of Environmental and Occupational Medicine
2024-12-01
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Series: | 环境与职业医学 |
Subjects: | |
Online Access: | http://www.jeom.org/article/cn/10.11836/JEOM24387 |
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