Constructing adverse outcome pathway for per- and polyfluoroalkyl substances and retinoblastoma based on PI3K-AKT/MAPK signaling pathway

Constructing adverse outcome pathway for per- and polyfluoroalkyl substances and retinoblastoma based on PI3K-AKT/MAPK signaling pathway

BackgroundExposure to per- and polyfluoroalkyl substances (PFAS) is associated with various cancers, and recent studies suggest it may also increase the risk of retinoblastoma (RB) in newborns. However, the pathogenic mechanisms remain unclear. ObjectiveBy constructing an adverse outcome pathway (AO...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuyan GUI, Tingji WANG, Minghao WANG, Yaqi XU, Yunhui ZHANG
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2024-12-01
Series:环境与职业医学
Subjects:
per- and polyfluoroalkyl substances
retinoblastoma
adverse outcome pathway
pi3k-akt/mapk signaling pathway
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM24387
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items