Oral abrocitinib in the treatment of granuloma annulare: a case report

Aim: To evaluate the therapeutic efficacy and safety of JAK inhibitor abrocitinib in patients with localized granuloma annulare (GA) and to review the available cases documented in English.Methods: We presented a patient who had a persistent, localized granuloma anulare (GA) for one year and did not...

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Main Authors: Wenyan Liu, Weifeng Chen, Xin Tian, Yihui Yu, Junhui Zhu, Jingyao Liang, Xibao Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/09546634.2024.2313090
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author Wenyan Liu
Weifeng Chen
Xin Tian
Yihui Yu
Junhui Zhu
Jingyao Liang
Xibao Zhang
author_facet Wenyan Liu
Weifeng Chen
Xin Tian
Yihui Yu
Junhui Zhu
Jingyao Liang
Xibao Zhang
author_sort Wenyan Liu
collection DOAJ
description Aim: To evaluate the therapeutic efficacy and safety of JAK inhibitor abrocitinib in patients with localized granuloma annulare (GA) and to review the available cases documented in English.Methods: We presented a patient who had a persistent, localized granuloma anulare (GA) for one year and did not respond to traditional therapies. This patient was treated with oral abrocitinib at a dosage of 150 mg daily.Results: After 6 weeks of treatment with abrocitinib, the patient exhibited notable symptom improvement with no new lesions. No adverse events or recurrences were reported during the 5-month follow-up period.Conclusions: Abrocitinib may be a promising and safe treatment option for patients with localized GA who do not respond to traditional therapies.
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institution Kabale University
issn 0954-6634
1471-1753
language English
publishDate 2024-12-01
publisher Taylor & Francis Group
record_format Article
series Journal of Dermatological Treatment
spelling doaj-art-a376a3474f0e4c57bac4f8b6f704ce892024-12-16T22:53:48ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532024-12-0135110.1080/09546634.2024.2313090Oral abrocitinib in the treatment of granuloma annulare: a case reportWenyan Liu0Weifeng Chen1Xin Tian2Yihui Yu3Junhui Zhu4Jingyao Liang5Xibao Zhang6Institute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaInstitute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaInstitute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaInstitute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaInstitute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaInstitute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaInstitute of Dermatology, Guangzhou Medical University, Guangzhou, P.R. ChinaAim: To evaluate the therapeutic efficacy and safety of JAK inhibitor abrocitinib in patients with localized granuloma annulare (GA) and to review the available cases documented in English.Methods: We presented a patient who had a persistent, localized granuloma anulare (GA) for one year and did not respond to traditional therapies. This patient was treated with oral abrocitinib at a dosage of 150 mg daily.Results: After 6 weeks of treatment with abrocitinib, the patient exhibited notable symptom improvement with no new lesions. No adverse events or recurrences were reported during the 5-month follow-up period.Conclusions: Abrocitinib may be a promising and safe treatment option for patients with localized GA who do not respond to traditional therapies.https://www.tandfonline.com/doi/10.1080/09546634.2024.2313090Granuloma annulareJAK inhibitorsabrocitinib
spellingShingle Wenyan Liu
Weifeng Chen
Xin Tian
Yihui Yu
Junhui Zhu
Jingyao Liang
Xibao Zhang
Oral abrocitinib in the treatment of granuloma annulare: a case report
Journal of Dermatological Treatment
Granuloma annulare
JAK inhibitors
abrocitinib
title Oral abrocitinib in the treatment of granuloma annulare: a case report
title_full Oral abrocitinib in the treatment of granuloma annulare: a case report
title_fullStr Oral abrocitinib in the treatment of granuloma annulare: a case report
title_full_unstemmed Oral abrocitinib in the treatment of granuloma annulare: a case report
title_short Oral abrocitinib in the treatment of granuloma annulare: a case report
title_sort oral abrocitinib in the treatment of granuloma annulare a case report
topic Granuloma annulare
JAK inhibitors
abrocitinib
url https://www.tandfonline.com/doi/10.1080/09546634.2024.2313090
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