Benefits and Safety of Empiric Antibiotic Treatment Active Against KPC-Producing <i>Klebsiella pneumoniae</i> for Febrile Neutropenic Episodes in Colonized Children with Acute Leukemia—An 8-Year Retrospective Observational Study

Benefits and Safety of Empiric Antibiotic Treatment Active Against KPC-Producing <i>Klebsiella pneumoniae</i> for Febrile Neutropenic Episodes in Colonized Children with Acute Leukemia—An 8-Year Retrospective Observational Study

In children with acute leukemia (AL), the mortality rate from <i>Klebsiella pneumoniae</i> carbapenemase (KPC)-producing <i>K. pneumoniae</i> bloodstream infection (KPC-KpBSI) exceeds 50%, highest when active treatment is delayed. Neutropenic KPC-<i>K. pneumoniae</i&...

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Bibliographic Details
Main Authors: Alessandra Micozzi, Cristina Luise, Chiara Lisi, Luisa Moleti, Stefania Santilli, Giuseppe Gentile
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antibiotics
Subjects:
children
acute leukemia
febrile neutropenia
KPC-<i>Klebsiella pneumoniae</i>
empiric antibiotic treatment
Online Access:https://www.mdpi.com/2079-6382/13/11/1017
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