Environment-sensitive turn-on fluorescent probe enables live cell imaging of myeloperoxidase activity during NETosis
Abstract Myeloperoxidase (MPO) plays an important role in the immune response of human neutrophils and has been implicated in autoimmune conditions, cardiovascular disorders, and neurodegeneration. Current methods to detect MPO activity rely on the detection of HOCl using activatable probes or requi...
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| Main Authors: | Enebie Ramos Cáceres, Lotte Kemperman, Kimberly M. Bonger |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-024-01338-5 |
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