Environment-sensitive turn-on fluorescent probe enables live cell imaging of myeloperoxidase activity during NETosis

Abstract Myeloperoxidase (MPO) plays an important role in the immune response of human neutrophils and has been implicated in autoimmune conditions, cardiovascular disorders, and neurodegeneration. Current methods to detect MPO activity rely on the detection of HOCl using activatable probes or requi...

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Bibliographic Details
Main Authors: Enebie Ramos Cáceres, Lotte Kemperman, Kimberly M. Bonger
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01338-5
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