Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients
Diabetes mellitus is a chronic disorder categorized by rise blood glucose with a disturbance in the use of carbohydrates, fats and proteins resulting from a deficiency in the secretion of the insulin or the action of insulin or both. The current study aimed to estimation of Vaspin and some biochem...
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College of science, university of Diyala
2024-01-01
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| Series: | Academic Science Journal |
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| Online Access: | https://acadscij.uodiyala.edu.iq/index.php/Home/article/view/351 |
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| author | Zahraa Abdalelah Saleem Khalid Shaalan Sahab |
| author_facet | Zahraa Abdalelah Saleem Khalid Shaalan Sahab |
| author_sort | Zahraa Abdalelah Saleem |
| collection | DOAJ |
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Diabetes mellitus is a chronic disorder categorized by rise blood glucose with a disturbance in the use of carbohydrates, fats and proteins resulting from a deficiency in the secretion of the insulin or the action of insulin or both. The current study aimed to estimation of Vaspin and some biochemical parameters included insulin, fasting blood glucose(FBG), HbA1c, urea, creatinine, Triglyceride(TG), Total Cholesterol(TC), High-density lipoprotein (HDL), low density lipoprotein (LDL) and Very low density lipoprotein (VLDL)in blood of type2 diabetic patients, and determining the change of the ratio in patients comparing with healthy people.The serum vaspin level in patients group was significantly lower than that of the healthy subjects (p<0.05). The serum insulin levels in patients were higher than of healthy subjects but without significant differences (p>0.05). There were a significant difference of serum FBG, HbA1c and urea levels in patients compared to controls (p<0.05), while creatinine level was increased non significantly (p>0.05). The levels of TC, TG, LDL and VLDL were elevated significantly in patients when compared with controls (p<0.05), while HDL was diminished non significantly in patients compared to controls. There was no significant links between serum vaspin and insulin concentrations with FBG, HbA1C, CRP, urea, creatinine, TC, TG, LDL, HDL, and VLDL levels. Vaspin had lowest area under curve (AUC 393. ) and sensitivity ( 68.3) in ROC curve.
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| format | Article |
| id | doaj-art-a30a7f8a045248d3a6694cc4e999b6df |
| institution | Kabale University |
| issn | 2958-4612 2959-5568 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | College of science, university of Diyala |
| record_format | Article |
| series | Academic Science Journal |
| spelling | doaj-art-a30a7f8a045248d3a6694cc4e999b6df2024-12-10T22:18:49ZengCollege of science, university of DiyalaAcademic Science Journal2958-46122959-55682024-01-012110.24237/ASJ.02.01.688BRelationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic PatientsZahraa Abdalelah SaleemKhalid Shaalan Sahab Diabetes mellitus is a chronic disorder categorized by rise blood glucose with a disturbance in the use of carbohydrates, fats and proteins resulting from a deficiency in the secretion of the insulin or the action of insulin or both. The current study aimed to estimation of Vaspin and some biochemical parameters included insulin, fasting blood glucose(FBG), HbA1c, urea, creatinine, Triglyceride(TG), Total Cholesterol(TC), High-density lipoprotein (HDL), low density lipoprotein (LDL) and Very low density lipoprotein (VLDL)in blood of type2 diabetic patients, and determining the change of the ratio in patients comparing with healthy people.The serum vaspin level in patients group was significantly lower than that of the healthy subjects (p<0.05). The serum insulin levels in patients were higher than of healthy subjects but without significant differences (p>0.05). There were a significant difference of serum FBG, HbA1c and urea levels in patients compared to controls (p<0.05), while creatinine level was increased non significantly (p>0.05). The levels of TC, TG, LDL and VLDL were elevated significantly in patients when compared with controls (p<0.05), while HDL was diminished non significantly in patients compared to controls. There was no significant links between serum vaspin and insulin concentrations with FBG, HbA1C, CRP, urea, creatinine, TC, TG, LDL, HDL, and VLDL levels. Vaspin had lowest area under curve (AUC 393. ) and sensitivity ( 68.3) in ROC curve. https://acadscij.uodiyala.edu.iq/index.php/Home/article/view/351T2Diabetes Mellitus, Vaspin, biochemical parameters, gender, BMI. |
| spellingShingle | Zahraa Abdalelah Saleem Khalid Shaalan Sahab Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients Academic Science Journal T2Diabetes Mellitus, Vaspin, biochemical parameters, gender, BMI. |
| title | Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients |
| title_full | Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients |
| title_fullStr | Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients |
| title_full_unstemmed | Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients |
| title_short | Relationship the Variation of Serum Vaspin and Some Biochemical Parameters Associated with Gender and BMI of Type2 Diabetic Patients |
| title_sort | relationship the variation of serum vaspin and some biochemical parameters associated with gender and bmi of type2 diabetic patients |
| topic | T2Diabetes Mellitus, Vaspin, biochemical parameters, gender, BMI. |
| url | https://acadscij.uodiyala.edu.iq/index.php/Home/article/view/351 |
| work_keys_str_mv | AT zahraaabdalelahsaleem relationshipthevariationofserumvaspinandsomebiochemicalparametersassociatedwithgenderandbmioftype2diabeticpatients AT khalidshaalansahab relationshipthevariationofserumvaspinandsomebiochemicalparametersassociatedwithgenderandbmioftype2diabeticpatients |