GVHD after CAR T-cell therapy post allogeneic hematopoietic cell transplantation — successfully treated by extracorporeal photopheresis

GVHD after CAR T-cell therapy post allogeneic hematopoietic cell transplantation — successfully treated by extracorporeal photopheresis

IntroductionCAR T-cell therapy is highly effective, but also associated with unique toxicities. Because of the origin of T cells in patients who previously underwent allogeneic hematopoietic cell transplantation (alloHCT), graft-versus-host disease (GVHD) in the post-CAR T-cell setting poses a relev...

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Bibliographic Details
Main Authors: Kiavasch Mohammad Nejad Farid, Gesine Bug, Anita Schmitt, Fabian Lang, Maria-Luisa Schubert, Uwe Haberkorn, Carsten Müller-Tidow, Peter Dreger, Michael Schmitt
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
graft-versus-host disease
CAR T-cell therapy
extracorporeal photopheresis
acute lymphoblastic leukemia
T-cell alloreactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1500177/full
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