The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study
BackgroundContinuous Positive Airway Pressure (CPAP) is an effective intervention for managing neonatal respiratory distress. However, its implementation encounters numerous challenges in resource-limited settings. It is imperative for healthcare professionals to devise highly practical and cost-eff...
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1534550/full |
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| author | Fanghua Qin Cuilan Dong Jun Qiu Qingqing Song Kumba Konomanyi Lucinda Sia Fatmata Sesay Aiqing Xiao |
| author_facet | Fanghua Qin Cuilan Dong Jun Qiu Qingqing Song Kumba Konomanyi Lucinda Sia Fatmata Sesay Aiqing Xiao |
| author_sort | Fanghua Qin |
| collection | DOAJ |
| description | BackgroundContinuous Positive Airway Pressure (CPAP) is an effective intervention for managing neonatal respiratory distress. However, its implementation encounters numerous challenges in resource-limited settings. It is imperative for healthcare professionals to devise highly practical and cost-effective modifications to CPAP systems to address these challenges.ObjectiveTo evaluate the clinical efficacy and operational feasibility of a modified bubble CPAP therapy utilizing locally available materials in reducing respiratory distress and improving survival rates of neonates in the Special Care Baby Unit (SCBU) of the Sierra Leone-China Friendship Hospital.Materials and methods93 neonates with respiratory distress were divided into the control group (n = 48) for nasal cannula oxygen therapy and the observation group (n = 45) for modified bubble CPAP therapy. The modified CPAP device was constructed using locally available materials, such as drinking cups and modified nasal cannulas, with oxygen delivered via concentrators. Respiratory Severity Score, blood oxygen saturation, heart rate, and respiration were monitored with data recorded at admission and 8 h after intervention.ResultsAfter intervention, the neonates in the observation group showed significant improvements in all parameters: decreased RSS scores (7.40 ± 0.986 vs. 5.33 ± 1.447, P < 0.001), heart rate (153.13 ± 5.998 vs. 141.60 ± 8.830, P < 0.001), and respiratory rate (47.87 ± 4.103 vs. 43.47 ± 3.833, P < 0.01), and higher oxygen saturation (73.60% ± 10.636% vs. 91.07% ± 8.940%, P < 0.001) and survival rate (88% vs. 62.5%, P < 0.01).ConclusionThe study indicated that the implementation of modified bubble CPAP therapy enhanced respiratory outcomes and increased survival rates among neonates experiencing respiratory distress in a resource-constrained setting in rural Sierra Leone. |
| format | Article |
| id | doaj-art-a2e8c1f57e9941b58a88f7eb2e424ea8 |
| institution | DOAJ |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Pediatrics |
| spelling | doaj-art-a2e8c1f57e9941b58a88f7eb2e424ea82025-08-20T03:13:29ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-04-011310.3389/fped.2025.15345501534550The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot studyFanghua Qin0Cuilan Dong1Jun Qiu2Qingqing Song3Kumba Konomanyi4Lucinda Sia Fatmata Sesay5Aiqing Xiao6Department of NICU, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha, Hunan, ChinaDepartment of NICU, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha, Hunan, ChinaPediatrics Research Institute of Hunan Province, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha, Hunan, ChinaDepartment of Cardiology, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha, Hunan, ChinaSCBU, Sierra Leone–China Friendship Hospital, Freetown, Sierra LeoneSCBU, Sierra Leone–China Friendship Hospital, Freetown, Sierra LeoneDepartment of NICU, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha, Hunan, ChinaBackgroundContinuous Positive Airway Pressure (CPAP) is an effective intervention for managing neonatal respiratory distress. However, its implementation encounters numerous challenges in resource-limited settings. It is imperative for healthcare professionals to devise highly practical and cost-effective modifications to CPAP systems to address these challenges.ObjectiveTo evaluate the clinical efficacy and operational feasibility of a modified bubble CPAP therapy utilizing locally available materials in reducing respiratory distress and improving survival rates of neonates in the Special Care Baby Unit (SCBU) of the Sierra Leone-China Friendship Hospital.Materials and methods93 neonates with respiratory distress were divided into the control group (n = 48) for nasal cannula oxygen therapy and the observation group (n = 45) for modified bubble CPAP therapy. The modified CPAP device was constructed using locally available materials, such as drinking cups and modified nasal cannulas, with oxygen delivered via concentrators. Respiratory Severity Score, blood oxygen saturation, heart rate, and respiration were monitored with data recorded at admission and 8 h after intervention.ResultsAfter intervention, the neonates in the observation group showed significant improvements in all parameters: decreased RSS scores (7.40 ± 0.986 vs. 5.33 ± 1.447, P < 0.001), heart rate (153.13 ± 5.998 vs. 141.60 ± 8.830, P < 0.001), and respiratory rate (47.87 ± 4.103 vs. 43.47 ± 3.833, P < 0.01), and higher oxygen saturation (73.60% ± 10.636% vs. 91.07% ± 8.940%, P < 0.001) and survival rate (88% vs. 62.5%, P < 0.01).ConclusionThe study indicated that the implementation of modified bubble CPAP therapy enhanced respiratory outcomes and increased survival rates among neonates experiencing respiratory distress in a resource-constrained setting in rural Sierra Leone.https://www.frontiersin.org/articles/10.3389/fped.2025.1534550/fullmodified bubble CPAPneonatal respiratory distressrespiratory supportresource-limited settingsclinical efficacy |
| spellingShingle | Fanghua Qin Cuilan Dong Jun Qiu Qingqing Song Kumba Konomanyi Lucinda Sia Fatmata Sesay Aiqing Xiao The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study Frontiers in Pediatrics modified bubble CPAP neonatal respiratory distress respiratory support resource-limited settings clinical efficacy |
| title | The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study |
| title_full | The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study |
| title_fullStr | The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study |
| title_full_unstemmed | The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study |
| title_short | The practice of a modified bubble CPAP therapy in a rural Sierra Leone SCBU-A pilot study |
| title_sort | practice of a modified bubble cpap therapy in a rural sierra leone scbu a pilot study |
| topic | modified bubble CPAP neonatal respiratory distress respiratory support resource-limited settings clinical efficacy |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1534550/full |
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