How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease

Background: Arterial embolization is a minimally invasive treatment that occludes blood vessels supplying pathological tissue. Developed to control bleeding without surgery, it has evolved over decades and is now applied in musculoskeletal oncology as a preoperative treatment, palliative care, or st...

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Main Authors: Nicolas Papalexis, Giuliano Peta, Michela Carta, Simone Quarchioni, Maddalena Di Carlo, Marco Miceli, Giancarlo Facchini
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Current Oncology
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Online Access:https://www.mdpi.com/1718-7729/31/12/555
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author Nicolas Papalexis
Giuliano Peta
Michela Carta
Simone Quarchioni
Maddalena Di Carlo
Marco Miceli
Giancarlo Facchini
author_facet Nicolas Papalexis
Giuliano Peta
Michela Carta
Simone Quarchioni
Maddalena Di Carlo
Marco Miceli
Giancarlo Facchini
author_sort Nicolas Papalexis
collection DOAJ
description Background: Arterial embolization is a minimally invasive treatment that occludes blood vessels supplying pathological tissue. Developed to control bleeding without surgery, it has evolved over decades and is now applied in musculoskeletal oncology as a preoperative treatment, palliative care, or standalone therapy for select tumors. Recently, its use has expanded globally in treating chronic pain syndromes and osteoarthritis. Materials and Methods: We reviewed the literature on arterial embolization in various musculoskeletal conditions. The focus was on established oncologic indications for primary and metastatic bone or soft tissue tumors, and emerging evidence on degenerative diseases like osteoarthritis, inflammatory musculoskeletal pathology, and intractable pain. Emphasis was placed on leading studies regarding efficacy, complications, and recurrence rates. Discussion: Arterial embolization has progressed from bleeding control to a versatile therapeutic option in musculoskeletal medicine. It offers symptom relief, reduces tumor size, and improves quality of life. Applications include oncologic interventions and management of degenerative and inflammatory conditions. Despite its benefits, variations in complications and recurrence rates highlight the need for standardized protocols and further research. Conclusions: Arterial embolization is a safe and effective minimally invasive tool in the multidisciplinary management of a wide range of musculoskeletal pathologies. Ongoing research is crucial to understand long-term efficacy, optimize protocols, and broaden its applications.
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series Current Oncology
spelling doaj-art-a2ababdd13cd4c55a1e40c16f7b6e2992024-12-27T14:19:57ZengMDPI AGCurrent Oncology1198-00521718-77292024-11-0131127523755410.3390/curroncol31120555How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal DiseaseNicolas Papalexis0Giuliano Peta1Michela Carta2Simone Quarchioni3Maddalena Di Carlo4Marco Miceli5Giancarlo Facchini6Department of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyDepartment of Diagnostic and Interventional Radiology, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, ItalyBackground: Arterial embolization is a minimally invasive treatment that occludes blood vessels supplying pathological tissue. Developed to control bleeding without surgery, it has evolved over decades and is now applied in musculoskeletal oncology as a preoperative treatment, palliative care, or standalone therapy for select tumors. Recently, its use has expanded globally in treating chronic pain syndromes and osteoarthritis. Materials and Methods: We reviewed the literature on arterial embolization in various musculoskeletal conditions. The focus was on established oncologic indications for primary and metastatic bone or soft tissue tumors, and emerging evidence on degenerative diseases like osteoarthritis, inflammatory musculoskeletal pathology, and intractable pain. Emphasis was placed on leading studies regarding efficacy, complications, and recurrence rates. Discussion: Arterial embolization has progressed from bleeding control to a versatile therapeutic option in musculoskeletal medicine. It offers symptom relief, reduces tumor size, and improves quality of life. Applications include oncologic interventions and management of degenerative and inflammatory conditions. Despite its benefits, variations in complications and recurrence rates highlight the need for standardized protocols and further research. Conclusions: Arterial embolization is a safe and effective minimally invasive tool in the multidisciplinary management of a wide range of musculoskeletal pathologies. Ongoing research is crucial to understand long-term efficacy, optimize protocols, and broaden its applications.https://www.mdpi.com/1718-7729/31/12/555arterial embolizationtherapeuticmusculoskeletal diseasesbone neoplasmssoft tissue neoplasmspalliative care
spellingShingle Nicolas Papalexis
Giuliano Peta
Michela Carta
Simone Quarchioni
Maddalena Di Carlo
Marco Miceli
Giancarlo Facchini
How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease
Current Oncology
arterial embolization
therapeutic
musculoskeletal diseases
bone neoplasms
soft tissue neoplasms
palliative care
title How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease
title_full How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease
title_fullStr How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease
title_full_unstemmed How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease
title_short How Arterial Embolization Is Transforming Treatment of Oncologic and Degenerative Musculoskeletal Disease
title_sort how arterial embolization is transforming treatment of oncologic and degenerative musculoskeletal disease
topic arterial embolization
therapeutic
musculoskeletal diseases
bone neoplasms
soft tissue neoplasms
palliative care
url https://www.mdpi.com/1718-7729/31/12/555
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