Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells
Abstract Dissection of the physiological interactomes of histone post-translational modifications (hPTMs) is crucial for understanding epigenetic regulatory pathways. Peptide- or protein-based histone photoaffinity tools expanded the ability to probe the epigenetic interactome, but in situ profiling...
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Main Authors: | Yu Wang, Jian Fan, Xianbin Meng, Qingyao Shu, Yincui Wu, Guo-Chao Chu, Rong Ji, Yinshan Ye, Xiangwei Wu, Jing Shi, Haiteng Deng, Lei Liu, Yi-Ming Li |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-55046-8 |
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