Hippocampal dysmetabolism contributes to cognitive loss in autoimmune encephalitis and focal temporal epilepsy

Hippocampal dysmetabolism contributes to cognitive loss in autoimmune encephalitis and focal temporal epilepsy

IntroductionAutoimmune encephalitis (AE) is associated with severe cognitive disability. Brain metabolic dysfunction has been linked to encephalopathy in neurodegenerative disorders; however, its role in the development of cognitive loss in AE has not been studied. We hypothesized that cognitively i...

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Bibliographic Details
Main Authors: Olga Taraschenko, Lakshman Arcot Jayagopal, Audrina Mullane, Kyle Greenman, Matthew White, Hesham Ghonim, Shelley Lee, Rana Khalil Zabad, Tracy Jasinski, Mariano Uberti
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
autoimmune encephalitis
temporal lobe epilepsy
cognitive loss
memory deficits
cerebral metabolism
myo-inositol
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1597928/full
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