Research progress of keratin in oral squamous cell carcinoma
Keratin (KRT) is one of the members of the cytoskeletal protein intermediate filament family mainly distributed in the cytoplasm of epithelial cells, which plays a significant role in maintaining the morphology of epithelial cells and intercellular connections. In addition, KRT also participates in...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Oral and Maxillofacial Surgery
2024-12-01
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| Series: | Kouqiang hemian waike zazhi |
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| Online Access: | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.06.009 |
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| _version_ | 1849225042916802560 |
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| author | WANG Xiaohu WANG Zuolin |
| author_facet | WANG Xiaohu WANG Zuolin |
| author_sort | WANG Xiaohu |
| collection | DOAJ |
| description | Keratin (KRT) is one of the members of the cytoskeletal protein intermediate filament family mainly distributed in the cytoplasm of epithelial cells, which plays a significant role in maintaining the morphology of epithelial cells and intercellular connections. In addition, KRT also participates in the occurrence and development of squamous cell carcinoma by regulating epithelial cell proliferation, migration, differentiation and epithelial-mesenchymal transformation (EMT). Oral squamous cell carcinoma (OSCC) is a common malignant tumor of the oral cavity which usually has a poor prognosis and low survival rate in patients. In recent years, the research on KRT in OSCC has gradually increased, and this paper expounds on the biological function of keratin and its research progress in OSCC. |
| format | Article |
| id | doaj-art-a2883e3a6dff4a28a9a51cbd50d086c3 |
| institution | Kabale University |
| issn | 1005-4979 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Journal of Oral and Maxillofacial Surgery |
| record_format | Article |
| series | Kouqiang hemian waike zazhi |
| spelling | doaj-art-a2883e3a6dff4a28a9a51cbd50d086c32025-08-25T06:11:31ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-12-0134647047210.12439/kqhm.1005-4979.2024.06.009Research progress of keratin in oral squamous cell carcinomaWANG Xiaohu0WANG Zuolin1Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral Implantology, Shanghai Tongji Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral Implantology, Shanghai Tongji Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaKeratin (KRT) is one of the members of the cytoskeletal protein intermediate filament family mainly distributed in the cytoplasm of epithelial cells, which plays a significant role in maintaining the morphology of epithelial cells and intercellular connections. In addition, KRT also participates in the occurrence and development of squamous cell carcinoma by regulating epithelial cell proliferation, migration, differentiation and epithelial-mesenchymal transformation (EMT). Oral squamous cell carcinoma (OSCC) is a common malignant tumor of the oral cavity which usually has a poor prognosis and low survival rate in patients. In recent years, the research on KRT in OSCC has gradually increased, and this paper expounds on the biological function of keratin and its research progress in OSCC.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.06.009keratinoral squamous cell carcinomaepithelial-mesenchymal transition |
| spellingShingle | WANG Xiaohu WANG Zuolin Research progress of keratin in oral squamous cell carcinoma Kouqiang hemian waike zazhi keratin oral squamous cell carcinoma epithelial-mesenchymal transition |
| title | Research progress of keratin in oral squamous cell carcinoma |
| title_full | Research progress of keratin in oral squamous cell carcinoma |
| title_fullStr | Research progress of keratin in oral squamous cell carcinoma |
| title_full_unstemmed | Research progress of keratin in oral squamous cell carcinoma |
| title_short | Research progress of keratin in oral squamous cell carcinoma |
| title_sort | research progress of keratin in oral squamous cell carcinoma |
| topic | keratin oral squamous cell carcinoma epithelial-mesenchymal transition |
| url | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.06.009 |
| work_keys_str_mv | AT wangxiaohu researchprogressofkeratininoralsquamouscellcarcinoma AT wangzuolin researchprogressofkeratininoralsquamouscellcarcinoma |