Use of Tissue Specimens from Stereotactic Biopsies for Patient-Derived GBM Organoid-Based Drug Testing

Use of Tissue Specimens from Stereotactic Biopsies for Patient-Derived GBM Organoid-Based Drug Testing

<i>IDH</i>-wildtype glioblastoma (GBM) represents the most common malignant form of brain tumor and is still incurable despite comprehensive therapeutic efforts. Due to tumor location and patient condition, open surgical resection of recurrent GBM is not always feasible. In these cases,...

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Main Authors: Amélie Wöllner, Adrian Paul, Maddalena Arquilla, Junguo Cao, Catharina Lotsch, Gerhard Jungwirth, Lena Jassowicz, Andreas von Deimling, Andreas W. Unterberg, Sandro M. Krieg, Martin Jakobs, Rolf Warta, Christel Herold-Mende
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
glioblastoma
patient-derived tumor organoids
stereotactic biopsy
precision medicine
Online Access:https://www.mdpi.com/2073-4409/14/10/701
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