CCL4 Affects Eosinophil Survival via the Shedding of the MUC1 N-Terminal Domain in Airway Inflammation

CCL4 Affects Eosinophil Survival via the Shedding of the MUC1 N-Terminal Domain in Airway Inflammation

Eosinophilic chronic rhinosinusitis (ECRS), a CRS with nasal polyps (CRSwNP), is characterized by eosinophilic infiltration with type 2 inflammation and is highly associated with bronchial asthma. Intractable ECRS with poorly controlled asthma is recognized as a difficult-to-treat eosinophilic airwa...

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Main Authors:	Yoshiki Kobayashi, Chu Hong Hanh, Naoto Yagi, Nhi Kieu Thi Le, Yasutaka Yun, Akihiro Shimamura, Kenta Fukui, Akitoshi Mitani, Kensuke Suzuki, Akira Kanda, Hiroshi Iwai
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Cells
Subjects:	airway epithelial cell bronchial asthma CCL4 chronic rhinosinusitis with nasal polyps eosinophilic chronic rhinosinusitis mucin glycoprotein 1
Online Access:	https://www.mdpi.com/2073-4409/14/1/33
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