Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility
Effects from aging in single cells are heterogenous, whereas at the organ- and tissue-levels aging phenotypes tend to appear as stereotypical changes. The mammary epithelium is a bilayer of two major phenotypically and functionally distinct cell lineages: luminal epithelial and myoepithelial cells....
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Main Authors: | Rosalyn W Sayaman, Masaru Miyano, Eric G Carlson, Parijat Senapati, Arrianna Zirbes, Sundus F Shalabi, Michael E Todhunter, Victoria E Seewaldt, Susan L Neuhausen, Martha R Stampfer, Dustin E Schones, Mark A LaBarge |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/95720 |
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