Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report

Guillain-Barré syndrome (GBS) is the most frequent cause of acute flaccid paralysis, and in two-thirds of the patients, antecedent infections have been identified. Brucellosis, a zoonotic disease, rarely leads to GBS. Herein, we present two patients with subacute brucellosis-induced GBS that were di...

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Main Authors: Mehrdad MORADI-PORDANJANI, Ameneh MEHRI-GHAHFARROKHI, Sohrab MORADI-PORDANJANI, Fereidoun RAHMANI
Format: Article
Language:Turkish
Published: Galenos Yayinevi 2025-01-01
Series:Mediterranean Journal of Infection, Microbes and Antimicrobials
Subjects:
Online Access:https://mjima.org/articles/subacute-brucellosis-induced-guillain-barre-syndrome-a-case-report/doi/mjima.galenos.2024.24139.2
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author Mehrdad MORADI-PORDANJANI
Ameneh MEHRI-GHAHFARROKHI
Sohrab MORADI-PORDANJANI
Fereidoun RAHMANI
author_facet Mehrdad MORADI-PORDANJANI
Ameneh MEHRI-GHAHFARROKHI
Sohrab MORADI-PORDANJANI
Fereidoun RAHMANI
author_sort Mehrdad MORADI-PORDANJANI
collection DOAJ
description Guillain-Barré syndrome (GBS) is the most frequent cause of acute flaccid paralysis, and in two-thirds of the patients, antecedent infections have been identified. Brucellosis, a zoonotic disease, rarely leads to GBS. Herein, we present two patients with subacute brucellosis-induced GBS that were diagnosed on the basis of their clinical course and electromyography and nerve conduction velocity study results. There was a 1-month and 5-month interval between the onset of brucellosis and GBS in the two patients. The patients recovered after undergoing plasma exchange, intravenous immunoglobulin administration, and antibiotic therapy. Our findings indicate that physicians should consider brucellosis as a potential etiology of GBS and closely monitor the neurological symptoms of patients with brucellosis.
format Article
id doaj-art-a2546eca3c4e4c6f8b0ec1ccc5a2b503
institution Kabale University
issn 2147-673X
language Turkish
publishDate 2025-01-01
publisher Galenos Yayinevi
record_format Article
series Mediterranean Journal of Infection, Microbes and Antimicrobials
spelling doaj-art-a2546eca3c4e4c6f8b0ec1ccc5a2b5032025-01-06T08:14:39ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2025-01-011412210.4274/mjima.galenos.2024.24139.2Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case ReportMehrdad MORADI-PORDANJANI0https://orcid.org/0000-0002-8944-7321Ameneh MEHRI-GHAHFARROKHI1https://orcid.org/0000-0001-9621-5716Sohrab MORADI-PORDANJANI2https://orcid.org/0009-0003-8977-0828Fereidoun RAHMANI3https://orcid.org/0000-0001-6929-6573Shahrekord University of Medical Sciences, Student Research Committee, Shahrekord, IranShahrekord University of Medical Sciences, Cellular and Molecular Research Center, Shahrekord, IranTehran University of Medical Sciences, Student Research Committee, Tehran, IranShahrekord University of Medical Sciences, Hajar Hospital, Department of Infectious Disease, Clinical Research Development Unit, Shahrekord, IranGuillain-Barré syndrome (GBS) is the most frequent cause of acute flaccid paralysis, and in two-thirds of the patients, antecedent infections have been identified. Brucellosis, a zoonotic disease, rarely leads to GBS. Herein, we present two patients with subacute brucellosis-induced GBS that were diagnosed on the basis of their clinical course and electromyography and nerve conduction velocity study results. There was a 1-month and 5-month interval between the onset of brucellosis and GBS in the two patients. The patients recovered after undergoing plasma exchange, intravenous immunoglobulin administration, and antibiotic therapy. Our findings indicate that physicians should consider brucellosis as a potential etiology of GBS and closely monitor the neurological symptoms of patients with brucellosis.https://mjima.org/articles/subacute-brucellosis-induced-guillain-barre-syndrome-a-case-report/doi/mjima.galenos.2024.24139.2brucellosisguillain-barré syndromeelectromyographyneurobrucellosis
spellingShingle Mehrdad MORADI-PORDANJANI
Ameneh MEHRI-GHAHFARROKHI
Sohrab MORADI-PORDANJANI
Fereidoun RAHMANI
Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report
Mediterranean Journal of Infection, Microbes and Antimicrobials
brucellosis
guillain-barré syndrome
electromyography
neurobrucellosis
title Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report
title_full Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report
title_fullStr Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report
title_full_unstemmed Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report
title_short Subacute Brucellosis-induced Guillain-Barré Syndrome: a Case Report
title_sort subacute brucellosis induced guillain barre syndrome a case report
topic brucellosis
guillain-barré syndrome
electromyography
neurobrucellosis
url https://mjima.org/articles/subacute-brucellosis-induced-guillain-barre-syndrome-a-case-report/doi/mjima.galenos.2024.24139.2
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AT amenehmehrighahfarrokhi subacutebrucellosisinducedguillainbarresyndromeacasereport
AT sohrabmoradipordanjani subacutebrucellosisinducedguillainbarresyndromeacasereport
AT fereidounrahmani subacutebrucellosisinducedguillainbarresyndromeacasereport