Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis

Abstract Purpose Interstitial cystitis (IC) or bladder pain syndrome (BPS) is a prevalent condition that presents the need to improve understanding of this ailment to facilitate treatment and diagnosis. However, the data regarding this syndrome is very limited for the Jordanian population. Therefore...

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Main Authors: Fadi Sawaqed, Mohammad Salem Hareedy, Malik Ayyad, Samer Al-Rawashdeh, Yousef M. Al‑saraireh
Format: Article
Language:English
Published: SpringerOpen 2025-08-01
Series:African Journal of Urology
Subjects:
Online Access:https://doi.org/10.1186/s12301-025-00517-7
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author Fadi Sawaqed
Mohammad Salem Hareedy
Malik Ayyad
Samer Al-Rawashdeh
Yousef M. Al‑saraireh
author_facet Fadi Sawaqed
Mohammad Salem Hareedy
Malik Ayyad
Samer Al-Rawashdeh
Yousef M. Al‑saraireh
author_sort Fadi Sawaqed
collection DOAJ
description Abstract Purpose Interstitial cystitis (IC) or bladder pain syndrome (BPS) is a prevalent condition that presents the need to improve understanding of this ailment to facilitate treatment and diagnosis. However, the data regarding this syndrome is very limited for the Jordanian population. Therefore, this study was centered around assessing symptom severity and how it correlates to gender. Methods Records of 147 patients diagnosed with IC/BPS between September 2014 and June 2019 in Karak Governmental Hospital were retrieved. Demographics and symptom severity information were also obtained. SPSS version 27 was used to carry out all statistical analyses and to determine the association between gender and symptom severity. Results 80.3% of the study population comprised women, and incidence remained unaffected with increasing age. Among symptoms, only urinary frequency (p = 0.018) and weaker urine flow (p = 0.002) were influenced by gender, and severity was significantly higher in males than females. Nocturia was the only symptom affected by age-related differences (p = 0.070). The analysis also revealed a statistically significant negative correlation between gender and nocturia (ρ = −0.196, p = 0.017), as well as between gender and weak urine flow (ρ = −0.251, p = 0.002). Conclusions IC/BPS is more prevalent in women. Age and gender at large do not affect symptom severity. Correlation analysis between gender and symptoms revealed that some symptoms, such as nocturia and weak urine flow, are likely to be more severe in men.
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spelling doaj-art-a1c3d30b485d4ab89a83c15afcc42c912025-08-20T03:43:22ZengSpringerOpenAfrican Journal of Urology1961-99872025-08-013111610.1186/s12301-025-00517-7Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysisFadi Sawaqed0Mohammad Salem Hareedy1Malik Ayyad2Samer Al-Rawashdeh3Yousef M. Al‑saraireh4Mutah universityMutah universityMutah universityMutah universityMutah universityAbstract Purpose Interstitial cystitis (IC) or bladder pain syndrome (BPS) is a prevalent condition that presents the need to improve understanding of this ailment to facilitate treatment and diagnosis. However, the data regarding this syndrome is very limited for the Jordanian population. Therefore, this study was centered around assessing symptom severity and how it correlates to gender. Methods Records of 147 patients diagnosed with IC/BPS between September 2014 and June 2019 in Karak Governmental Hospital were retrieved. Demographics and symptom severity information were also obtained. SPSS version 27 was used to carry out all statistical analyses and to determine the association between gender and symptom severity. Results 80.3% of the study population comprised women, and incidence remained unaffected with increasing age. Among symptoms, only urinary frequency (p = 0.018) and weaker urine flow (p = 0.002) were influenced by gender, and severity was significantly higher in males than females. Nocturia was the only symptom affected by age-related differences (p = 0.070). The analysis also revealed a statistically significant negative correlation between gender and nocturia (ρ = −0.196, p = 0.017), as well as between gender and weak urine flow (ρ = −0.251, p = 0.002). Conclusions IC/BPS is more prevalent in women. Age and gender at large do not affect symptom severity. Correlation analysis between gender and symptoms revealed that some symptoms, such as nocturia and weak urine flow, are likely to be more severe in men.https://doi.org/10.1186/s12301-025-00517-7Interstitial cystitisBladder pain syndromeSymptomsSuprapubic painNocturia
spellingShingle Fadi Sawaqed
Mohammad Salem Hareedy
Malik Ayyad
Samer Al-Rawashdeh
Yousef M. Al‑saraireh
Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis
African Journal of Urology
Interstitial cystitis
Bladder pain syndrome
Symptoms
Suprapubic pain
Nocturia
title Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis
title_full Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis
title_fullStr Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis
title_full_unstemmed Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis
title_short Patterns of symptoms and severity of interstitial cystitis/bladder pain syndrome: a clinical analysis
title_sort patterns of symptoms and severity of interstitial cystitis bladder pain syndrome a clinical analysis
topic Interstitial cystitis
Bladder pain syndrome
Symptoms
Suprapubic pain
Nocturia
url https://doi.org/10.1186/s12301-025-00517-7
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