Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools
Worldwide, there has been an increasing prevalence of kidney disorders for several years. Kidney disorders are characterized by abnormal kidney biomarkers like uric acid, urea, cystatin C, creatinine, kidney injury molecule-1, C-related protein, etc., in the human body. A person suffering from kidne...
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KeAi Communications Co., Ltd.
2024-01-01
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| Series: | Sensors International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S266635112300027X |
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| author | Neelam Yadav Jagriti Narang Anil Kumar Chhillar Jogender Singh Rana Mohd Usman Mohd Siddique El-Refaie Kenawy Saad Alkahtani Mohd Neyaz Ahsan Amit Kumar Nayak Md Saquib Hasnain |
| author_facet | Neelam Yadav Jagriti Narang Anil Kumar Chhillar Jogender Singh Rana Mohd Usman Mohd Siddique El-Refaie Kenawy Saad Alkahtani Mohd Neyaz Ahsan Amit Kumar Nayak Md Saquib Hasnain |
| author_sort | Neelam Yadav |
| collection | DOAJ |
| description | Worldwide, there has been an increasing prevalence of kidney disorders for several years. Kidney disorders are characterized by abnormal kidney biomarkers like uric acid, urea, cystatin C, creatinine, kidney injury molecule-1, C-related protein, etc., in the human body. A person suffering from kidney disorders is prone to several other serious health consequences, such as cardiac diseases and renal failure, which can lead to death. However, early diagnosis of kidney disorders requires effective disease management to prevent disease progression. Existing diagnostic techniques used for monitoring kidney biomarker concentration include chromatographic assays, spectroscopic assays, immunoassays, magnetic resonance imaging (MRI), computed tomography (CT), etc. They also necessitate equipped laboratory infrastructure, specific instruments, highly trained personnel working on these instruments, and monitoring kidney patients. Hence, these are expensive and time-consuming. Since the past few decades, a number of biosensors, like electrochemical, optical, immunosensors, potentiometric, colorimetric, etc., have been used to overcome the drawbacks of conventional and modern techniques. These biosensing systems have many benefits, such as being cost-effective, quick, simple, highly sensitive, specific, requiring a minimum sample amount, reliable, and easy to miniaturize. This review article discusses the uses of effectual biosensors for kidney biomarker detection with their potential advantages and disadvantages. Future research needs to be implicated in developing highly advanced biosensors that must be sensitive, economical, and simple so that they can be used for on-site early detection of kidney biomarkers to assess kidney function. |
| format | Article |
| id | doaj-art-a1c1c651b77e40f68b7501e832f561af |
| institution | Kabale University |
| issn | 2666-3511 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Sensors International |
| spelling | doaj-art-a1c1c651b77e40f68b7501e832f561af2025-01-04T04:57:05ZengKeAi Communications Co., Ltd.Sensors International2666-35112024-01-015100253Diagnostic methods employing kidney biomarkers clinching biosensors as promising toolsNeelam Yadav0Jagriti Narang1Anil Kumar Chhillar2Jogender Singh Rana3Mohd Usman Mohd Siddique4El-Refaie Kenawy5Saad Alkahtani6Mohd Neyaz Ahsan7Amit Kumar Nayak8Md Saquib Hasnain9Department of Biochemistry, Central University of Haryana, Jant-Pali, Mahendergarh, 123029, India; Centre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana, 124001, IndiaDepartment of Biotechnology, Jamia Hamdard University, New Delhi, 110025, IndiaCentre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana, 124001, IndiaDepartment of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat, Haryana, 131039, IndiaDepartment of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal’s Institute of Pharmacy, Dhule, Maharastra, 424001, IndiaPolymer Research Group, Chemistry Department, Faculty of Science, Tanta University, Tanta, EgyptDepartment of Zoology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi ArabiaDepartment of Medical Laboratory Technology, University Polytechnic, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, IndiaDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India; Corresponding author.Corresponding author.; Department of Biochemistry, Central University of Haryana, Jant-Pali, Mahendergarh, 123029, India; Centre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana, 124001, India; Department of Biotechnology, Jamia Hamdard University, New Delhi, 110025, India; Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat, Haryana, 131039, India; Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal’s Institute of Pharmacy, Dhule, Maharastra, 424001, India; Polymer Research Group, Chemistry Department, Faculty of Science, Tanta University, Tanta, Egypt; Department of Zoology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia; Department of Medical Laboratory Technology, University Polytechnic, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India; Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India; Department of Pharmacy, Palamau Institute of Pharmacy, Chianki, Daltonganj, 822102, Jharkhand, IndiaWorldwide, there has been an increasing prevalence of kidney disorders for several years. Kidney disorders are characterized by abnormal kidney biomarkers like uric acid, urea, cystatin C, creatinine, kidney injury molecule-1, C-related protein, etc., in the human body. A person suffering from kidney disorders is prone to several other serious health consequences, such as cardiac diseases and renal failure, which can lead to death. However, early diagnosis of kidney disorders requires effective disease management to prevent disease progression. Existing diagnostic techniques used for monitoring kidney biomarker concentration include chromatographic assays, spectroscopic assays, immunoassays, magnetic resonance imaging (MRI), computed tomography (CT), etc. They also necessitate equipped laboratory infrastructure, specific instruments, highly trained personnel working on these instruments, and monitoring kidney patients. Hence, these are expensive and time-consuming. Since the past few decades, a number of biosensors, like electrochemical, optical, immunosensors, potentiometric, colorimetric, etc., have been used to overcome the drawbacks of conventional and modern techniques. These biosensing systems have many benefits, such as being cost-effective, quick, simple, highly sensitive, specific, requiring a minimum sample amount, reliable, and easy to miniaturize. This review article discusses the uses of effectual biosensors for kidney biomarker detection with their potential advantages and disadvantages. Future research needs to be implicated in developing highly advanced biosensors that must be sensitive, economical, and simple so that they can be used for on-site early detection of kidney biomarkers to assess kidney function.http://www.sciencedirect.com/science/article/pii/S266635112300027XKidney diseasesBiomarkersBiosensorsAcute phaseDiagnosis |
| spellingShingle | Neelam Yadav Jagriti Narang Anil Kumar Chhillar Jogender Singh Rana Mohd Usman Mohd Siddique El-Refaie Kenawy Saad Alkahtani Mohd Neyaz Ahsan Amit Kumar Nayak Md Saquib Hasnain Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools Sensors International Kidney diseases Biomarkers Biosensors Acute phase Diagnosis |
| title | Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools |
| title_full | Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools |
| title_fullStr | Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools |
| title_full_unstemmed | Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools |
| title_short | Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools |
| title_sort | diagnostic methods employing kidney biomarkers clinching biosensors as promising tools |
| topic | Kidney diseases Biomarkers Biosensors Acute phase Diagnosis |
| url | http://www.sciencedirect.com/science/article/pii/S266635112300027X |
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