Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems

Abstract Autocatalysis is thought to have played an important role in the earliest stages of the origin of life. An autocatalytic cycle (AC) is a set of reactions that results in stoichiometric increase in its constituent chemicals. When the reactions of multiple interacting ACs are active in a regi...

Full description

Saved in:
Bibliographic Details
Main Authors: Alex M. Plum, Christopher P. Kempes, Zhen Peng, David A. Baum
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Complexity
Online Access:https://doi.org/10.1038/s44260-025-00045-z
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849335229223796736
author Alex M. Plum
Christopher P. Kempes
Zhen Peng
David A. Baum
author_facet Alex M. Plum
Christopher P. Kempes
Zhen Peng
David A. Baum
author_sort Alex M. Plum
collection DOAJ
description Abstract Autocatalysis is thought to have played an important role in the earliest stages of the origin of life. An autocatalytic cycle (AC) is a set of reactions that results in stoichiometric increase in its constituent chemicals. When the reactions of multiple interacting ACs are active in a region of space, they can have interactions analogous to those between species in biological ecosystems. Prior studies of autocatalytic chemical ecosystems (ACEs) have suggested avenues for accumulating complexity, such as ecological succession, as well as obstacles such as competitive exclusion. We extend this ecological framework to investigate the effects of surface adsorption, desorption, and diffusion on ACE ecology. Simulating ACEs as particle-based stochastic reaction-diffusion systems in spatial environments—including open, two-dimensional reaction-diffusion systems and adsorptive mineral surfaces—we demonstrate that spatial structure can enhance ACE diversity by (i) permitting otherwise mutually exclusive ACs to coexist and (ii) subjecting new AC traits to selection.
format Article
id doaj-art-a18a639ae16b48e8b88331317e7620e0
institution Kabale University
issn 2731-8753
language English
publishDate 2025-07-01
publisher Nature Portfolio
record_format Article
series npj Complexity
spelling doaj-art-a18a639ae16b48e8b88331317e7620e02025-08-20T03:45:22ZengNature Portfolionpj Complexity2731-87532025-07-01211810.1038/s44260-025-00045-zSpatial structure supports diversity in prebiotic autocatalytic chemical ecosystemsAlex M. Plum0Christopher P. Kempes1Zhen Peng2David A. Baum3Department of Physics, University of California San DiegoThe Santa Fe InstituteWisconsin Institute for Discovery, University of Wisconsin-MadisonWisconsin Institute for Discovery, University of Wisconsin-MadisonAbstract Autocatalysis is thought to have played an important role in the earliest stages of the origin of life. An autocatalytic cycle (AC) is a set of reactions that results in stoichiometric increase in its constituent chemicals. When the reactions of multiple interacting ACs are active in a region of space, they can have interactions analogous to those between species in biological ecosystems. Prior studies of autocatalytic chemical ecosystems (ACEs) have suggested avenues for accumulating complexity, such as ecological succession, as well as obstacles such as competitive exclusion. We extend this ecological framework to investigate the effects of surface adsorption, desorption, and diffusion on ACE ecology. Simulating ACEs as particle-based stochastic reaction-diffusion systems in spatial environments—including open, two-dimensional reaction-diffusion systems and adsorptive mineral surfaces—we demonstrate that spatial structure can enhance ACE diversity by (i) permitting otherwise mutually exclusive ACs to coexist and (ii) subjecting new AC traits to selection.https://doi.org/10.1038/s44260-025-00045-z
spellingShingle Alex M. Plum
Christopher P. Kempes
Zhen Peng
David A. Baum
Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
npj Complexity
title Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
title_full Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
title_fullStr Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
title_full_unstemmed Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
title_short Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
title_sort spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems
url https://doi.org/10.1038/s44260-025-00045-z
work_keys_str_mv AT alexmplum spatialstructuresupportsdiversityinprebioticautocatalyticchemicalecosystems
AT christopherpkempes spatialstructuresupportsdiversityinprebioticautocatalyticchemicalecosystems
AT zhenpeng spatialstructuresupportsdiversityinprebioticautocatalyticchemicalecosystems
AT davidabaum spatialstructuresupportsdiversityinprebioticautocatalyticchemicalecosystems