Applications and translational research advances of degradable implantable hydrogels
Degradable implantable hydrogels have become a research hotspot in various fields, including wound sealing, hemostasis, tissue regeneration, smart biosensors, and drug delivery systems. This is attributed to their ability to degrade and absorb in a controlled manner after achieving their intended in...
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| Format: | Article |
| Language: | zho |
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Lanzhou University Press
2024-12-01
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| Series: | 生物医学转化 |
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| Online Access: | http://swyxzh.ijournals.cn/swyxzh/article/html/20240407 |
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| author | Wang Qimeng Yu Lisha Mao Zhengwei |
| author_facet | Wang Qimeng Yu Lisha Mao Zhengwei |
| author_sort | Wang Qimeng |
| collection | DOAJ |
| description | Degradable implantable hydrogels have become a research hotspot in various fields, including wound sealing, hemostasis, tissue regeneration, smart biosensors, and drug delivery systems. This is attributed to their ability to degrade and absorb in a controlled manner after achieving their intended in vivo effects, thereby avoiding the risks associated with long-term implantation and secondary surgeries. However, although extensive fundamental research has been conducted on degradable implantable hydrogels, successful cases of clinical translation remain relatively rare. This review systematically summarizes and analyzes the research advances in degradable implantable hydrogels. It focuses on the structures and types of hydrogels, advances in clinical research, and examples of translational applications. Furthermore, it discusses translational pathways in clinical applications and market potential of these materials. This review aims to provide valuable insights and references for promoting the clinical translation of degradable implantable hydrogels, thereby contributing to the development of this field. |
| format | Article |
| id | doaj-art-a15f4bacc8214ff1aa0d9e275d84ef68 |
| institution | Kabale University |
| issn | 2096-8965 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Lanzhou University Press |
| record_format | Article |
| series | 生物医学转化 |
| spelling | doaj-art-a15f4bacc8214ff1aa0d9e275d84ef682025-01-13T07:36:08ZzhoLanzhou University Press生物医学转化2096-89652024-12-01545864,6910.12287/j.issn.2096-8965.20240407Applications and translational research advances of degradable implantable hydrogelsWang Qimeng0Yu Lisha1Mao Zhengwei2Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058 , Zhejiang, ChinaKey Laboratory of Precision Diagnosis and Treatment of Hepatobiliary and Pancreatic Tumor of Zhejiang Province,The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou 310009 , Zhejiang, ChinaDepartment of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058 , Zhejiang, China ；Key Laboratory of Precision Diagnosis and Treatment of Hepatobiliary and Pancreatic Tumor of Zhejiang Province,The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou 310009 , Zhejiang, ChinaDegradable implantable hydrogels have become a research hotspot in various fields, including wound sealing, hemostasis, tissue regeneration, smart biosensors, and drug delivery systems. This is attributed to their ability to degrade and absorb in a controlled manner after achieving their intended in vivo effects, thereby avoiding the risks associated with long-term implantation and secondary surgeries. However, although extensive fundamental research has been conducted on degradable implantable hydrogels, successful cases of clinical translation remain relatively rare. This review systematically summarizes and analyzes the research advances in degradable implantable hydrogels. It focuses on the structures and types of hydrogels, advances in clinical research, and examples of translational applications. Furthermore, it discusses translational pathways in clinical applications and market potential of these materials. This review aims to provide valuable insights and references for promoting the clinical translation of degradable implantable hydrogels, thereby contributing to the development of this field.http://swyxzh.ijournals.cn/swyxzh/article/html/20240407degradable implantable hydrogelstranslation researchsealing and hemostasistissue engineeringbiosensorsdrug carrier |
| spellingShingle | Wang Qimeng Yu Lisha Mao Zhengwei Applications and translational research advances of degradable implantable hydrogels 生物医学转化 degradable implantable hydrogels translation research sealing and hemostasis tissue engineering biosensors drug carrier |
| title | Applications and translational research advances of degradable implantable hydrogels |
| title_full | Applications and translational research advances of degradable implantable hydrogels |
| title_fullStr | Applications and translational research advances of degradable implantable hydrogels |
| title_full_unstemmed | Applications and translational research advances of degradable implantable hydrogels |
| title_short | Applications and translational research advances of degradable implantable hydrogels |
| title_sort | applications and translational research advances of degradable implantable hydrogels |
| topic | degradable implantable hydrogels translation research sealing and hemostasis tissue engineering biosensors drug carrier |
| url | http://swyxzh.ijournals.cn/swyxzh/article/html/20240407 |
| work_keys_str_mv | AT wangqimeng applicationsandtranslationalresearchadvancesofdegradableimplantablehydrogels AT yulisha applicationsandtranslationalresearchadvancesofdegradableimplantablehydrogels AT maozhengwei applicationsandtranslationalresearchadvancesofdegradableimplantablehydrogels |