Xenotransplantation of Human Umbilical Mesenchymal Stromal Cells Derived from Wharton's Jelly Mitigates Mouse Amyotrophic Lateral Sclerosis

Abstract Background Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of motor neurons in the cerebral cortex, brainstem, and spinal cord, eventually leading to paralysis, respiratory failure, and death. Currently, no effective treatment exists f...

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Bibliographic Details
Main Authors: Chun-Fu Lin, Yu-Hui Chen, Chang-Ching Yeh, Sanford P. C. Hsu, Yu-Show Fu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
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Online Access:https://doi.org/10.1186/s13287-025-04485-1
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