EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in Pseudomonas aeruginosa

EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in Pseudomonas aeruginosa

ABSTRACT The human pathogen Pseudomonas aeruginosa (Pa) poses a major risk for a range of severe infections, particularly lung infections in patients suffering from cystic fibrosis (CF). As previously reported, the virulent behavior of this pathogen is enhanced by elevated levels of Ca2+ that are co...

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Bibliographic Details
Main Authors: Jacob Burch-Konda, Biraj B. Kayastha, Myriam Achour, Aya Kubo, Mackenzie Hull, Reygan Braga, Lorelei Winton, Rendi R. Rogers, Erika I. Lutter, Marianna A. Patrauchan
Format: Article
Language:English
Published: American Society for Microbiology 2024-11-01
Series:mBio
Subjects:
transcription
calcium signaling
promoter activity
pyoverdine
RNA seq
virulence
Online Access:https://journals.asm.org/doi/10.1128/mbio.02447-24
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