Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients
Abstract Background Large contact areas between the grafted bone and the bony endplate (BEP) can optimize the load transmission pattern and decrease the risk of non-union and cage subsidence. The relationship between endplate morphology parameters and complications may stem from the difference in co...
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BMC
2025-08-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-025-09036-6 |
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| author | Xiao Hu Haiying Fu Run Lin Liyu Ran Xingrui Peng Tianhang Xie Jiancheng Zeng |
| author_facet | Xiao Hu Haiying Fu Run Lin Liyu Ran Xingrui Peng Tianhang Xie Jiancheng Zeng |
| author_sort | Xiao Hu |
| collection | DOAJ |
| description | Abstract Background Large contact areas between the grafted bone and the bony endplate (BEP) can optimize the load transmission pattern and decrease the risk of non-union and cage subsidence. The relationship between endplate morphology parameters and complications may stem from the difference in contact sufficiency between the grafted bone and BEP. This study was conducted to verify that changes in endplate morphology affect the risk of complications in patients with oblique lumbar interbody fusion (OLIF) by changing the grafted bony occupancy rate (GBOR). Methods Imaging data of 95 segments of 75 patients who underwent OLIF were collected retrospectively. Endplate morphology parameters, GBOR values, and complications were measured by computational tomography (CT). Results The superior endplate was more concave than the inferior endplate was. The GBOR values in the superior endplate were significantly lower than those in the inferior endplate (coronal and sagittal). The relationship between endplate morphology parameters and GBOR values was significant. The nonfusion rate was significantly higher in the superior endplate. A lower GBOR is an independent predictor of non-union and more severe cage subsidence. Conclusions Changes in endplate morphology affect the risk of cage subsidence and non-union in patients undergoing OLIF by changing the GBOR. Newly designed OLIF cages with larger concave depths on the superior side and different concave angles should be promoted to optimize the match between the grafted bone and the BEP and improve the prognosis of patients with OLIF. |
| format | Article |
| id | doaj-art-a0f0b5ad73cc4c879143ea7f57cad47f |
| institution | Kabale University |
| issn | 1471-2474 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
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| series | BMC Musculoskeletal Disorders |
| spelling | doaj-art-a0f0b5ad73cc4c879143ea7f57cad47f2025-08-20T03:42:41ZengBMCBMC Musculoskeletal Disorders1471-24742025-08-0126111110.1186/s12891-025-09036-6Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patientsXiao Hu0Haiying Fu1Run Lin2Liyu Ran3Xingrui Peng4Tianhang Xie5Jiancheng Zeng6Frontiers Science Center for Disease-related Molecular Network, Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan UniversityDepartment of Orthopedic Surgery, West China Hospital, West China School of Nursing, Sichuan UniversityDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan UniversityDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan UniversityDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan UniversityDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan UniversityDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan UniversityAbstract Background Large contact areas between the grafted bone and the bony endplate (BEP) can optimize the load transmission pattern and decrease the risk of non-union and cage subsidence. The relationship between endplate morphology parameters and complications may stem from the difference in contact sufficiency between the grafted bone and BEP. This study was conducted to verify that changes in endplate morphology affect the risk of complications in patients with oblique lumbar interbody fusion (OLIF) by changing the grafted bony occupancy rate (GBOR). Methods Imaging data of 95 segments of 75 patients who underwent OLIF were collected retrospectively. Endplate morphology parameters, GBOR values, and complications were measured by computational tomography (CT). Results The superior endplate was more concave than the inferior endplate was. The GBOR values in the superior endplate were significantly lower than those in the inferior endplate (coronal and sagittal). The relationship between endplate morphology parameters and GBOR values was significant. The nonfusion rate was significantly higher in the superior endplate. A lower GBOR is an independent predictor of non-union and more severe cage subsidence. Conclusions Changes in endplate morphology affect the risk of cage subsidence and non-union in patients undergoing OLIF by changing the GBOR. Newly designed OLIF cages with larger concave depths on the superior side and different concave angles should be promoted to optimize the match between the grafted bone and the BEP and improve the prognosis of patients with OLIF.https://doi.org/10.1186/s12891-025-09036-6Oblique lumbar interbody fusionGrafted bony occupancy rateEndplate morphologyNon-unionCage subsidence |
| spellingShingle | Xiao Hu Haiying Fu Run Lin Liyu Ran Xingrui Peng Tianhang Xie Jiancheng Zeng Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients BMC Musculoskeletal Disorders Oblique lumbar interbody fusion Grafted bony occupancy rate Endplate morphology Non-union Cage subsidence |
| title | Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients |
| title_full | Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients |
| title_fullStr | Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients |
| title_full_unstemmed | Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients |
| title_short | Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients |
| title_sort | endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in olif patients |
| topic | Oblique lumbar interbody fusion Grafted bony occupancy rate Endplate morphology Non-union Cage subsidence |
| url | https://doi.org/10.1186/s12891-025-09036-6 |
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