Adeno-Associated Virus-Engineered Umbilical Cord-Derived Mesenchymal Stromal Cells Overexpressing Human sFlt-1 for Anti-Angiogenesis

Adeno-Associated Virus-Engineered Umbilical Cord-Derived Mesenchymal Stromal Cells Overexpressing Human sFlt-1 for Anti-Angiogenesis

Purpose. Genetic engineering of mesenchymal stromal cells (MSCs) using viral vectors has emerged as a promising approach to enhance the efficacy of anti-angiogenic gene therapies. Umbilical cord-derived MSCs are an attractive cell source due to their easy accessibility and potential for genetic modi...

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Bibliographic Details
Main Authors: Ewa Yee-Wa Choy, Chee-Onn Leong, Soon-Keng Cheong, Khong-Lek Then, Kong-Yong Then
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Life
Subjects:
mesenchymal stromal cells
adeno-associated virus
genetic engineering
anti-angiogenesis
Online Access:https://www.mdpi.com/2075-1729/15/5/728
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