Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study
Background: Perceived cognitive impairments(PCI) are the most common complications that Non-Central Nervous System (Non-CNS) cancers survivors experience. Studies have suggested that those who expreience fear of cancer recurrence (FCR) tend to report cognitive problems; however, this association has...
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| Format: | Article |
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Taylor & Francis Group
2023-01-01
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| Series: | Preventive Oncology & Epidemiology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/28322134.2023.2292359 |
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| author | Yesol Yang Eric M. McLaughlin Michelle J. Naughton Diane Von Ah Nazmus Saquib Judith E. Carroll Lihong Qi Dorothy S. Lane Tonya S. Orchard Electra D. Paskett |
| author_facet | Yesol Yang Eric M. McLaughlin Michelle J. Naughton Diane Von Ah Nazmus Saquib Judith E. Carroll Lihong Qi Dorothy S. Lane Tonya S. Orchard Electra D. Paskett |
| author_sort | Yesol Yang |
| collection | DOAJ |
| description | Background: Perceived cognitive impairments(PCI) are the most common complications that Non-Central Nervous System (Non-CNS) cancers survivors experience. Studies have suggested that those who expreience fear of cancer recurrence (FCR) tend to report cognitive problems; however, this association has not been examined.Methods: Participants (n = 6,714) were enrolled in the Women’s Health Initiative Life and Longevity After Cancer study. FCR was assessed using the Cancer Worry Scale and PCI was assessed using the PCI subscale of FACT-Cog. The association between FCR and PCI was analyzed using univariable and multivariable logistic regression models. A cut off score of [Formula: see text] 14 is indicative of high FCR and below 14 indicating low FCR. Scores lower than 60 indicated PCI.Result: The multivariable model showed that higher FCR corresponded to an increase in odds of PCI (OR = 1.15, p<0.001). We also found that older age at diagnosis (p<0.001), less social support (p = 0.01), over ten pounds of weight gain after cancer treatment (p = 0.02), and mild or worse anxiety (p<0.001) were also associated with increased odds of PCI from the multivariable analysis.Discussion: Our findings indicate that survivors with higher FCR demonstrated poorer cognitive performance than those with lower FCR. These results suggest that those with higher FCR are more likely to report PCI. |
| format | Article |
| id | doaj-art-a0d809db37a5455b928830a89188d009 |
| institution | Kabale University |
| issn | 2832-2134 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Preventive Oncology & Epidemiology |
| spelling | doaj-art-a0d809db37a5455b928830a89188d0092024-11-27T07:14:08ZengTaylor & Francis GroupPreventive Oncology & Epidemiology2832-21342023-01-011110.1080/28322134.2023.2292359Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer StudyYesol Yang0Eric M. McLaughlin1Michelle J. Naughton2Diane Von Ah3Nazmus Saquib4Judith E. Carroll5Lihong Qi6Dorothy S. Lane7Tonya S. Orchard8Electra D. Paskett9Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH, USAThe Ohio State University, Center for Biostatistics, Columbus, OH, USADivision of Cancer Prevention and Control, Department of Medicine, College of Medicine, The Ohio State University, Columbus, OH, USADivision of Cancer Prevention and Control, Department of Medicine, College of Medicine, The Ohio State University, Columbus, OH, USACollege of Medicine, Sulaiman AlRajhi University, Albukairiyah, Saudi ArabiaDepartment of Psychiatry, Cousins Center for Psychoneuroimmunology, University of California Los Angeles, David Geffen School of Medicine, Jane & Terry Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USADepartment of Public Health Sciences, School of Medicine, University of California Davis, Davis, CA, USADepartment of Family, Population & Preventive Medicine, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USAHuman Nutrition Program, Department of Human Sciences, College of Education and Human Ecology, The Ohio State University, Columbus, OH, USADepartment of Internal Medicine, The Ohio State University Comprehensive Cancer Center-James, Columbus, OH, USABackground: Perceived cognitive impairments(PCI) are the most common complications that Non-Central Nervous System (Non-CNS) cancers survivors experience. Studies have suggested that those who expreience fear of cancer recurrence (FCR) tend to report cognitive problems; however, this association has not been examined.Methods: Participants (n = 6,714) were enrolled in the Women’s Health Initiative Life and Longevity After Cancer study. FCR was assessed using the Cancer Worry Scale and PCI was assessed using the PCI subscale of FACT-Cog. The association between FCR and PCI was analyzed using univariable and multivariable logistic regression models. A cut off score of [Formula: see text] 14 is indicative of high FCR and below 14 indicating low FCR. Scores lower than 60 indicated PCI.Result: The multivariable model showed that higher FCR corresponded to an increase in odds of PCI (OR = 1.15, p<0.001). We also found that older age at diagnosis (p<0.001), less social support (p = 0.01), over ten pounds of weight gain after cancer treatment (p = 0.02), and mild or worse anxiety (p<0.001) were also associated with increased odds of PCI from the multivariable analysis.Discussion: Our findings indicate that survivors with higher FCR demonstrated poorer cognitive performance than those with lower FCR. These results suggest that those with higher FCR are more likely to report PCI.https://www.tandfonline.com/doi/10.1080/28322134.2023.2292359CognitionFear of cancer recurrenceCancer survivorsCognitionOlder women |
| spellingShingle | Yesol Yang Eric M. McLaughlin Michelle J. Naughton Diane Von Ah Nazmus Saquib Judith E. Carroll Lihong Qi Dorothy S. Lane Tonya S. Orchard Electra D. Paskett Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study Preventive Oncology & Epidemiology Cognition Fear of cancer recurrence Cancer survivors Cognition Older women |
| title | Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study |
| title_full | Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study |
| title_fullStr | Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study |
| title_full_unstemmed | Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study |
| title_short | Fear of Cancer Recurrence Associated with Perceived Cognitive Impairment among Women with Cancers: Findings from the Women’s Health Initiative Life and Longevity After Cancer Study |
| title_sort | fear of cancer recurrence associated with perceived cognitive impairment among women with cancers findings from the women s health initiative life and longevity after cancer study |
| topic | Cognition Fear of cancer recurrence Cancer survivors Cognition Older women |
| url | https://www.tandfonline.com/doi/10.1080/28322134.2023.2292359 |
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