Asperulosidic acid inhibits the PI3K/Akt/NF-κB pathway to suppress endotoxin-induced uveitis

Asperulosidic acid inhibits the PI3K/Akt/NF-κB pathway to suppress endotoxin-induced uveitis

IntroductionUveitis, a severe inflammatory disease affecting the uvea, is associated with visual impairment and irreversible blindness. Asperulosidic Acid (ASPA), derived from Hedyotis diffusa, is known for its notable anti-inflammatory and antioxidant characteristics.MethodsThe present study explor...

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Bibliographic Details
Main Authors: Yong Du, Jing Lu, Lujia Feng, Long Zhao, Ping Wu, Yuxia He, Linbin Zhou, Xing Wang, Hui Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
uveitis
asperulosidic acid
EIU
inflammation
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1524779/full
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