Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations

Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations

Abstract Background: Mesenchymal stem cells (MSCs) derived from gestational tissues offer a promising avenue for prenatal intervention in congenital malformations although their application is hampered by concerns related to cellular plasticity and the need for invasive, high-risk surgical procedure...

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Main Authors: Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
Exosomes
Mimetics
Congenital malformations
mRNA therapeutics
Ex vivo embryo culture
Online Access:https://doi.org/10.1186/s13287-024-04082-8
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