Modulation of Kv Channel Gating by Light-Controlled Membrane Thickness

Modulation of Kv Channel Gating by Light-Controlled Membrane Thickness

Voltage-gated potassium (Kv) channels are e ssential for shaping action potentials and rely on anionic lipids for proper gating, yet the mechanistic basis of lipid–channel interactions remains unclear. Cryo-electron microscopy studies suggest that, in the down state, arginine residues of the voltage...

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Bibliographic Details
Main Authors: Rohit Yadav, Juergen Pfeffermann, Nikolaus Goessweiner-Mohr, Toma Glasnov, Sergey A. Akimov, Peter Pohl
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomolecules
Subjects:
Kv channel
voltage sensor
photoswitchable lipids
electrophysiology
Online Access:https://www.mdpi.com/2218-273X/15/5/744
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