Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection

Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection

Abstract Background The Porcine Epidemic Diarrhea Virus (PEDV) is one of the major challenges facing the global pig farming industry, and vaccines and treatments have proven difficult in controlling its spread. Faecalibacterium prausnitzii (F.prausnitzii), a key commensal bacterium in the gut, has b...

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Main Authors: JunHong Xing, TianMing Niu, Tong Yu, BoShi Zou, ChunWei Shi, YingJie Wang, ShuHui Fan, MingHan Li, MeiYing Bao, Yu Sun, KuiPeng Gao, JingJing Qiu, DongXing Zhang, Nan Wang, YanLong Jiang, HaiBin Huang, Xin Cao, Yan Zeng, JianZhong Wang, ShuMin Zhang, JingTao Hu, Di Zhang, WuSheng Sun, GuiLian Yang, WenTao Yang, ChunFeng Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Microbiome
Subjects:
PEDV
F.prausnitzii
OMVs
Gut microbiota
Phosphatidylcholine
Online Access:https://doi.org/10.1186/s40168-025-02078-x
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