The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis
Abstract Introduction The Atopic Dermatitis Control Tool (ADCT) assesses six concepts regarding patient-perceived control of atopic dermatitis (AD) in adults and adolescents with AD. This study aimed to develop two modified ADCT versions, one for children with AD aged 8–11 years and another for care...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Adis, Springer Healthcare
2024-11-01
|
| Series: | Dermatology and Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s13555-024-01289-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846148051462258688 |
|---|---|
| author | Chien-Chia Chuang David M. Pariser Eric Simpson Jennifer Dine Michelle Brown Sheri Fehnel Zhixiao Wang |
| author_facet | Chien-Chia Chuang David M. Pariser Eric Simpson Jennifer Dine Michelle Brown Sheri Fehnel Zhixiao Wang |
| author_sort | Chien-Chia Chuang |
| collection | DOAJ |
| description | Abstract Introduction The Atopic Dermatitis Control Tool (ADCT) assesses six concepts regarding patient-perceived control of atopic dermatitis (AD) in adults and adolescents with AD. This study aimed to develop two modified ADCT versions, one for children with AD aged 8–11 years and another for caregivers of children with AD aged 6 months to 11 years. Methods Following the US Food and Drug Administration patient-reported outcomes guidance, the ADCT was modified to produce draft Child and Caregiver ADCT versions, maintaining the original six concepts. The instruments were refined and finalized through an iterative process using input from children with AD and caregivers of children with AD via qualitative interviews. Inclusion criteria were clinician diagnosis of AD, prescription treatment use in the past 3 months, and itching/scratching or rash in the past month. Interviews consisted of concept elicitation to identify perceptions of AD control and cognitive debriefing to test and refine the ADCT items. Results In total, 19 children (mean age 9.2 years, 74% male) and 17 caregivers (mean age 36.3 years, 100% female) were interviewed. During concept elicitation, children and caregivers reported similar symptoms and described the cycling and unpredictability of AD. Most participants reported that daily activities were impacted negatively by AD symptoms. The concept of AD control resonated with children and caregivers, and respondents were able to describe their experiences related to AD symptom severity. Children were unfamiliar with the term AD, so the Child ADCT version was named the Child Eczema Control Tool (ECT). Children and caregivers both reported that the instruments assessed relevant concepts, comprehensively measured AD control, and demonstrated content and face validity. Conclusions The Child ECT and Caregiver ADCT were developed and qualitatively validated for assessing AD control in patients aged 6 months to 11 years and may offer simple ways to assess disease control and optimize treatment decisions. Video Abstract |
| format | Article |
| id | doaj-art-a0a1c152957c426abfd8533e6d30fad7 |
| institution | Kabale University |
| issn | 2193-8210 2190-9172 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Dermatology and Therapy |
| spelling | doaj-art-a0a1c152957c426abfd8533e6d30fad72024-12-01T12:10:41ZengAdis, Springer HealthcareDermatology and Therapy2193-82102190-91722024-11-0114123261327110.1007/s13555-024-01289-8The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic DermatitisChien-Chia Chuang0David M. Pariser1Eric Simpson2Jennifer Dine3Michelle Brown4Sheri Fehnel5Zhixiao Wang6SanofiEastern Virginia Medical School and Virginia Clinical Research IncOregon Health and Science UniversityResearch Triangle Institute Health Solutions, Research Triangle ParkResearch Triangle Institute Health Solutions, Research Triangle ParkResearch Triangle Institute Health Solutions, Research Triangle ParkRegeneron Pharmaceuticals IncAbstract Introduction The Atopic Dermatitis Control Tool (ADCT) assesses six concepts regarding patient-perceived control of atopic dermatitis (AD) in adults and adolescents with AD. This study aimed to develop two modified ADCT versions, one for children with AD aged 8–11 years and another for caregivers of children with AD aged 6 months to 11 years. Methods Following the US Food and Drug Administration patient-reported outcomes guidance, the ADCT was modified to produce draft Child and Caregiver ADCT versions, maintaining the original six concepts. The instruments were refined and finalized through an iterative process using input from children with AD and caregivers of children with AD via qualitative interviews. Inclusion criteria were clinician diagnosis of AD, prescription treatment use in the past 3 months, and itching/scratching or rash in the past month. Interviews consisted of concept elicitation to identify perceptions of AD control and cognitive debriefing to test and refine the ADCT items. Results In total, 19 children (mean age 9.2 years, 74% male) and 17 caregivers (mean age 36.3 years, 100% female) were interviewed. During concept elicitation, children and caregivers reported similar symptoms and described the cycling and unpredictability of AD. Most participants reported that daily activities were impacted negatively by AD symptoms. The concept of AD control resonated with children and caregivers, and respondents were able to describe their experiences related to AD symptom severity. Children were unfamiliar with the term AD, so the Child ADCT version was named the Child Eczema Control Tool (ECT). Children and caregivers both reported that the instruments assessed relevant concepts, comprehensively measured AD control, and demonstrated content and face validity. Conclusions The Child ECT and Caregiver ADCT were developed and qualitatively validated for assessing AD control in patients aged 6 months to 11 years and may offer simple ways to assess disease control and optimize treatment decisions. Video Abstracthttps://doi.org/10.1007/s13555-024-01289-8Atopic dermatitisPatient-reported outcomesADCTDisease controlPediatric AD patients |
| spellingShingle | Chien-Chia Chuang David M. Pariser Eric Simpson Jennifer Dine Michelle Brown Sheri Fehnel Zhixiao Wang The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis Dermatology and Therapy Atopic dermatitis Patient-reported outcomes ADCT Disease control Pediatric AD patients |
| title | The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis |
| title_full | The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis |
| title_fullStr | The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis |
| title_full_unstemmed | The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis |
| title_short | The Atopic Dermatitis Control Tool: Adaptation and Content Validation for Children and Caregivers of Children with Atopic Dermatitis |
| title_sort | atopic dermatitis control tool adaptation and content validation for children and caregivers of children with atopic dermatitis |
| topic | Atopic dermatitis Patient-reported outcomes ADCT Disease control Pediatric AD patients |
| url | https://doi.org/10.1007/s13555-024-01289-8 |
| work_keys_str_mv | AT chienchiachuang theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT davidmpariser theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT ericsimpson theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT jenniferdine theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT michellebrown theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT sherifehnel theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT zhixiaowang theatopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT chienchiachuang atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT davidmpariser atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT ericsimpson atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT jenniferdine atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT michellebrown atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT sherifehnel atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis AT zhixiaowang atopicdermatitiscontroltooladaptationandcontentvalidationforchildrenandcaregiversofchildrenwithatopicdermatitis |