NT2-derived astrocyte–neuron co-culture reflects physiological relevance and offers research validity

NT2-derived astrocyte–neuron co-culture reflects physiological relevance and offers research validity

Abstract Background Obtaining human neurons and astrocytes for in vitro studies presents a significant challenge owing to the complexity of replicating their development and functionality outside the human brain. The Ntera-2 cell line is a valuable source of human neurons and astrocytes in neuroscie...

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Main Authors: Sylwia Kedracka-Krok, Ewelina Fic, Zuzanna Cepil, Piotr Rybczyński, Agata Szlaga, Radosław Cacała, Sławomir Lasota, Anna Blasiak, Marta Dziedzicka-Wasylewska
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Ntera-2
NT2
Human neurons
Human astrocytes
Co-culture
Proteome
Online Access:https://doi.org/10.1186/s11658-025-00765-z
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