Proline‐rich transmembrane protein 2 regulates the magnitude and frequency of dopamine release by repetitive neuronal stimuli in the striatum of L‐dopa‐treated mice
Abstract Mutations in proline‐rich transmembrane protein 2 (PRRT2) cause paroxysmal kinesigenic dyskinesia (PKD). Recently, we reported that a Prrt2 mutation exacerbated L‐dopa‐induced motor deficits in mice, suggesting that the basal ganglia might contribute to PKD pathology. Here, we demonstrated...
Saved in:
Main Authors: | Daisuke Hatta, Shiho Makiya, Kaito Kanamoto, Kaori Watanabe, Yuki Fuchigami, Shigeru Kawakami, Akira Kinoshita, Koh‐Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2024-12-01
|
Series: | Neuropsychopharmacology Reports |
Subjects: | |
Online Access: | https://doi.org/10.1002/npr2.12478 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The effect of L-dopa and DBS on cortical oscillations in Parkinson's disease analyzed by hidden Markov model algorithm
by: Kunzhou Wei, et al.
Published: (2025-01-01) -
Effect of Grovth Medium on L-Dopa and Dopamine Production Using Citrobacter freundii (NRRL B-2643)
by: Sinan Saydam, et al.
Published: (2022-12-01) -
l-Tyrosine and l-DOPA: Promising scaffolds for the synthesis of biologically active compounds
by: Ndayiragije, Euphrem, et al.
Published: (2024-11-01) -
Case report: Resolution of VIPoma-related symptoms with peptide receptor radionuclide therapy
by: Turgut Bora Cengiz, et al.
Published: (2025-01-01) -
“Rosary Sign” at Somatostatin Receptor PET in a Case of Recurrent Meningioma
by: Cesare Michele Iacovitti, et al.
Published: (2024-11-01)