Modeling tumor relapse using proliferation tracing and ablation transgenic mouse

Abstract Tumor relapse remains a significant obstacle to successful therapy. Preclinical animal models that accurately reflect tumor relapse in patients are urgently needed. Here, we employed a dual recombinase-mediated genetic system to genetically trace and ablate proliferating cells in a polyomav...

Full description

Saved in:
Bibliographic Details
Main Authors: Chuang Zhao, Xin-nan Zheng, Han-ying Huang, Lin Tian
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00792-1
Tags: Add Tag
No Tags, Be the first to tag this record!