COMPARATIVE ANALYSIS OF REFERENCE-BASED CELL TYPE MAPPING AND MANUAL ANNOTATION IN SINGLE CELL RNA SEQUENCING ANALYSIS

COMPARATIVE ANALYSIS OF REFERENCE-BASED CELL TYPE MAPPING AND MANUAL ANNOTATION IN SINGLE CELL RNA SEQUENCING ANALYSIS

Single-cell RNA sequencing (scRNA-seq) offers unprecedented insight into cellular diversity in complex tissues like peripheral blood mononuclear cells (PBMC). Furthermore, differential gene expression at a single-cell level can provide a basis for understanding the specialized roles of individual c...

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Bibliographic Details
Main Authors: Larisa Goričan, Boris Gole, Gregor Jezernik, Gloria Krajnc, Uroš Potočnik, Mario Gorenjak
Format: Article
Language:English
Published: University of Ljubljana Press (Založba Univerze v Ljubljani) 2024-12-01
Series:Slovenian Veterinary Research
Subjects:
single-cell transcriptomics
peripheral blood mononuclear cells
reference mapping
cell-type annotation
immune system
Online Access:https://www.slovetres.si/index.php/SVR/article/view/1920
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