The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients
Background: Type 2 diabetes mellitus (T2DM) is a major health problem worldwide. As glycemic control worsens, the risk of both microvascular and macrovascular complications increases. . The aim of this study was to investigate the relationship between blood glucose regulation and two different par...
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Selcuk University Press
2024-04-01
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| Series: | Genel Tıp Dergisi |
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| author | Semra Özkan Öztürk Seval Müzeyyen Ecin |
| author_facet | Semra Özkan Öztürk Seval Müzeyyen Ecin |
| author_sort | Semra Özkan Öztürk |
| collection | DOAJ |
| description | Background: Type 2 diabetes mellitus (T2DM) is a major health problem worldwide. As glycemic control worsens, the risk of both microvascular and macrovascular complications increases. . The aim of this study was to investigate the relationship between blood glucose regulation and two different parameters: uric acid/HDL ratio (UHR) and monocyte/HDL ratio (MHR) in male subjects with type 2 diabetes.
Methods: In this retrospective study, a total of 166 male patients diagnosed with type 2 diabetes and 83 healthy adult men as a control cohort were included. Diabetic male participants were equally divided into two subgroups: the group with uncontrolled blood glucose (HbA1c levels exceeding 7, n=83) and the group with good glycemic control (HbA1c levels at or below 7, n=83). Our analysis included assessment of several serum markers, including triglyceride, high-density lipoprotein (HDL), uric acid, low-density lipoprotein (LDL), neutrophil, lymphocyte, monocyte, white blood cell, hemoglobin and platelet levels. In addition, uric acid/HDL ratio, body mass index and monocyte/HDL ratio were compared.
Results: Creatinine levels were normal in all study participants and ages were similar in the groups. Triglyceride levels were significantly higher in diabetic patients compared to the healthy group (P |
| format | Article |
| id | doaj-art-a033f2bae2db4cfaac0a2a6114ef8d21 |
| institution | Kabale University |
| issn | 2602-3741 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj-art-a033f2bae2db4cfaac0a2a6114ef8d212025-01-03T00:46:51ZengSelcuk University PressGenel Tıp Dergisi2602-37412024-04-0134220721110.54005/geneltip.1366271154The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic PatientsSemra Özkan Öztürk0Seval Müzeyyen Ecin1Mersin Şehir Eğitim ve Araştırma HastanesiMersin Şehir Eğitim ve Araştırma HastanesiBackground: Type 2 diabetes mellitus (T2DM) is a major health problem worldwide. As glycemic control worsens, the risk of both microvascular and macrovascular complications increases. . The aim of this study was to investigate the relationship between blood glucose regulation and two different parameters: uric acid/HDL ratio (UHR) and monocyte/HDL ratio (MHR) in male subjects with type 2 diabetes. Methods: In this retrospective study, a total of 166 male patients diagnosed with type 2 diabetes and 83 healthy adult men as a control cohort were included. Diabetic male participants were equally divided into two subgroups: the group with uncontrolled blood glucose (HbA1c levels exceeding 7, n=83) and the group with good glycemic control (HbA1c levels at or below 7, n=83). Our analysis included assessment of several serum markers, including triglyceride, high-density lipoprotein (HDL), uric acid, low-density lipoprotein (LDL), neutrophil, lymphocyte, monocyte, white blood cell, hemoglobin and platelet levels. In addition, uric acid/HDL ratio, body mass index and monocyte/HDL ratio were compared. Results: Creatinine levels were normal in all study participants and ages were similar in the groups. Triglyceride levels were significantly higher in diabetic patients compared to the healthy group (Phttps://dergipark.org.tr/tr/download/article-file/3433178ip 2 diyabetürik asit/hdl oranımonosit/hdl oranıhba1ctype 2 diabetes mellitusuric acid/hdl ratiomonocyte/hdl ratiohba1c |
| spellingShingle | Semra Özkan Öztürk Seval Müzeyyen Ecin The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients Genel Tıp Dergisi ip 2 diyabet ürik asit/hdl oranı monosit/hdl oranı hba1c type 2 diabetes mellitus uric acid/hdl ratio monocyte/hdl ratio hba1c |
| title | The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients |
| title_full | The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients |
| title_fullStr | The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients |
| title_full_unstemmed | The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients |
| title_short | The Relationship Between Uric Acid/HDL Ratio and Monocyte/HDL Ratio and Glycemic Control in Male Type 2 Diabetic Patients |
| title_sort | relationship between uric acid hdl ratio and monocyte hdl ratio and glycemic control in male type 2 diabetic patients |
| topic | ip 2 diyabet ürik asit/hdl oranı monosit/hdl oranı hba1c type 2 diabetes mellitus uric acid/hdl ratio monocyte/hdl ratio hba1c |
| url | https://dergipark.org.tr/tr/download/article-file/3433178 |
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