A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan
A carbon-paste electrode modified with ferrocenecarboxaldehyde and NiO nanoparticle (NiO/NPs) was used for the sensitive and selective voltammetric determination of cysteamine in the presence of tryptophan. The oxidation of cysteamine at the modified electrode was investigated by cyclic voltammetry...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/946230 |
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| author | Hassan Karimi-Maleh Maryam Salimi-Amiri Fatemeh Karimi Mohammad A. Khalilzadeh Mehdi Baghayeri |
| author_facet | Hassan Karimi-Maleh Maryam Salimi-Amiri Fatemeh Karimi Mohammad A. Khalilzadeh Mehdi Baghayeri |
| author_sort | Hassan Karimi-Maleh |
| collection | DOAJ |
| description | A carbon-paste electrode modified with ferrocenecarboxaldehyde and NiO nanoparticle (NiO/NPs) was used for the sensitive and selective voltammetric determination of cysteamine in the presence of tryptophan. The oxidation of cysteamine at the modified electrode was investigated by cyclic voltammetry (CV), chronoamperometry, and square-wave voltammetry (SWV). The values of the catalytic rate constant () and diffusion coefficient () for cysteamine were calculated. The modified electrode exhibits an efficient electron-mediating behavior together with well-separated oxidation peaks for cysteamine and tryptophan. At the optimum pH of 7.0 in a 0.1 M phosphate buffer solution, the SWV anodic peak currents showed a linear relationship versus cysteamine concentrations in the range of 0.09–300.0 µM and a detection limit of 0.06 µM. Finally, the proposed method was also examined as a selective, simple, and precise electrochemical sensor for the determination of cysteamine in real samples such as urine and capsule. |
| format | Article |
| id | doaj-art-a011cf966d5444b8a07db635e0d55cc4 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-a011cf966d5444b8a07db635e0d55cc42025-02-03T01:03:47ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/946230946230A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of TryptophanHassan Karimi-Maleh0Maryam Salimi-Amiri1Fatemeh Karimi2Mohammad A. Khalilzadeh3Mehdi Baghayeri4Department of Chemistry, Science and Research Branch, Islamic Azad University, Mazandaran, IranDepartment of Physics, Sari Branch, Islamic Azad University, Sari, IranDepartment of Chemistry, Science and Research Branch, Islamic Azad University, Mazandaran, IranDepartment of Chemistry, Science and Research Branch, Islamic Azad University, Mazandaran, IranDepartment of Chemistry, Faculty of Science, Hakim Sabzevari University, P.O. Box 397, Sabzevar, IranA carbon-paste electrode modified with ferrocenecarboxaldehyde and NiO nanoparticle (NiO/NPs) was used for the sensitive and selective voltammetric determination of cysteamine in the presence of tryptophan. The oxidation of cysteamine at the modified electrode was investigated by cyclic voltammetry (CV), chronoamperometry, and square-wave voltammetry (SWV). The values of the catalytic rate constant () and diffusion coefficient () for cysteamine were calculated. The modified electrode exhibits an efficient electron-mediating behavior together with well-separated oxidation peaks for cysteamine and tryptophan. At the optimum pH of 7.0 in a 0.1 M phosphate buffer solution, the SWV anodic peak currents showed a linear relationship versus cysteamine concentrations in the range of 0.09–300.0 µM and a detection limit of 0.06 µM. Finally, the proposed method was also examined as a selective, simple, and precise electrochemical sensor for the determination of cysteamine in real samples such as urine and capsule.http://dx.doi.org/10.1155/2013/946230 |
| spellingShingle | Hassan Karimi-Maleh Maryam Salimi-Amiri Fatemeh Karimi Mohammad A. Khalilzadeh Mehdi Baghayeri A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan Journal of Chemistry |
| title | A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan |
| title_full | A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan |
| title_fullStr | A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan |
| title_full_unstemmed | A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan |
| title_short | A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan |
| title_sort | voltammetric sensor based on nio nanoparticle modified carbon paste electrode for determination of cysteamine in the presence of high concentration of tryptophan |
| url | http://dx.doi.org/10.1155/2013/946230 |
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