Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes
Background: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear. Aim: To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data. Methods: A re...
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| Language: | English |
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Bioscientifica
2025-01-01
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| Series: | European Thyroid Journal |
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| Online Access: | https://etj.bioscientifica.com/view/journals/etj/14/1/ETJ-24-0176.xml |
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| author | Elpida Demetriou Aliki Economides Maria Fokou Demetris Lamnisos Stavroula A Paschou Panagiotis Papageorgis Panayiotis A Economides |
| author_facet | Elpida Demetriou Aliki Economides Maria Fokou Demetris Lamnisos Stavroula A Paschou Panagiotis Papageorgis Panayiotis A Economides |
| author_sort | Elpida Demetriou |
| collection | DOAJ |
| description | Background: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear. Aim: To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data. Methods: A retrospective cohort study of 310 patients with thyroid nodules was performed. Patients were categorized based on their BMI, and grayscale US data and fine-needle aspiration cytology results were evaluated. Results: Patients with BMI ≥ 25 kg/m2 were found to have a higher number of thyroid nodules compared to those with BMI < 25 kg/m2 (4.25 ± 2.42 vs 3.66 ± 1.93) (P value = 0.05). Patients with BMI ≥ 25 kg/m2 had more suspicious and malignant cytology than those with BMI < 25 kg/m2 (P value = 0.029). Patients with BMI ≥ 25 kg/m2 had more nodules with intermediate and high suspicion sonographic patterns. However, this did not reach statistical significance. Conclusion: Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy. |
| format | Article |
| id | doaj-art-9ff553d67ae540d198139b85448cc3ad |
| institution | Kabale University |
| issn | 2235-0802 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | European Thyroid Journal |
| spelling | doaj-art-9ff553d67ae540d198139b85448cc3ad2025-01-12T04:28:53ZengBioscientificaEuropean Thyroid Journal2235-08022025-01-0114110.1530/ETJ-24-01761Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomesElpida Demetriou0Aliki Economides1Maria Fokou2Demetris Lamnisos3Stavroula A Paschou4Panagiotis Papageorgis5Panayiotis A Economides6Department of Medicine, School of Medicine, European University Cyprus, Nicosia, CyprusEconomides Thyroid & Endocrinology Center, Nicosia, CyprusDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, CyprusDepartment of Life Sciences, European University Cyprus, Nicosia, CyprusDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, CyprusDepartment of Life Sciences, European University Cyprus, Nicosia, CyprusDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, CyprusBackground: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear. Aim: To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data. Methods: A retrospective cohort study of 310 patients with thyroid nodules was performed. Patients were categorized based on their BMI, and grayscale US data and fine-needle aspiration cytology results were evaluated. Results: Patients with BMI ≥ 25 kg/m2 were found to have a higher number of thyroid nodules compared to those with BMI < 25 kg/m2 (4.25 ± 2.42 vs 3.66 ± 1.93) (P value = 0.05). Patients with BMI ≥ 25 kg/m2 had more suspicious and malignant cytology than those with BMI < 25 kg/m2 (P value = 0.029). Patients with BMI ≥ 25 kg/m2 had more nodules with intermediate and high suspicion sonographic patterns. However, this did not reach statistical significance. Conclusion: Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy.https://etj.bioscientifica.com/view/journals/etj/14/1/ETJ-24-0176.xmlthyroid nodulesobesitybmithyroid ultrasoundfnaadiposity |
| spellingShingle | Elpida Demetriou Aliki Economides Maria Fokou Demetris Lamnisos Stavroula A Paschou Panagiotis Papageorgis Panayiotis A Economides Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes European Thyroid Journal thyroid nodules obesity bmi thyroid ultrasound fna adiposity |
| title | Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes |
| title_full | Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes |
| title_fullStr | Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes |
| title_full_unstemmed | Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes |
| title_short | Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes |
| title_sort | adiposity is associated with a higher number of thyroid nodules and worse fine needle aspiration outcomes |
| topic | thyroid nodules obesity bmi thyroid ultrasound fna adiposity |
| url | https://etj.bioscientifica.com/view/journals/etj/14/1/ETJ-24-0176.xml |
| work_keys_str_mv | AT elpidademetriou adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes AT alikieconomides adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes AT mariafokou adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes AT demetrislamnisos adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes AT stavroulaapaschou adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes AT panagiotispapageorgis adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes AT panayiotisaeconomides adiposityisassociatedwithahighernumberofthyroidnodulesandworsefineneedleaspirationoutcomes |